Methods and a probes are disclosed for vaginal tactile and electromyographic imaging, and location-guided female pelvic floor therapy. Methods include the steps of inserting a vaginal probe equipped with tactile sensors and electrodes acting as electromyographic sensors into a vagina along a vaginal canal to separate apart two opposing vaginal walls, recording a tactile response and an electromyographic response from at least one of two opposing vaginal walls during pelvic floor muscle contraction, determining locations along the vaginal canal for delivery of therapy based on presence of tactile response above a predetermined tactile threshold and/or presence of electromyographic response above a predetermined EMG threshold along the vaginal probe, selecting at least one of target locations to be used for location-guided therapy, and applying the therapy such as electrical muscle stimulation to at least one of selected locations using the same electrodes at these locations. The probe comprises a probe housing, a tactile sensors array, a plurality of electrodes which can be used as an electromyography array or as an electric muscle stimulation array, and at least one reference electrode.

Disclosed is an extensible electrode array (102) for accurately locating a pelvic floor muscle, and its design method and an extensible pelvic floor electrode. The design method includes: (1) obtaining a three-dimensional muscle anatomy map of a pelvic floor muscle, dividing a muscle according to the three-dimensional muscle anatomy map and determining a muscle fiber trend, and for each muscle, determining a plurality of three-dimensional coordinate points for marking each muscle along the muscle fiber trend (S101); (2) after projecting all three-dimensional coordinate projects onto a two-dimensional plane unfolded in a shape of an elastic cavity (101), taking each two-dimensional coordinate point in the two-dimensional plane as a location to dispose an electrode plate (S102); (3) simulating a mechanical property of the elastic cavity (101), and determining a deformation rate of an extensible electrode wire (105) of the electrode plate when the extensible electrode wire (105) of the electrode plate is arranged along a muscle fiber direction of the pelvic floor muscle (S103); and (4) according to a design result, mounting the electrode plate and the extensible electrode wire (105) on the elastic cavity (101) to form the extensible electrode array (102) (S104). The design method enables each electrode plate to locate the pelvic floor muscle before and after expansion, thereby improving accuracy in collecting a myoelectric signal of the pelvic floor muscle.

A device and method for treating female urinary incontinence and also for treating fecal incontinence are presented. A fractional RF grid array is used to heat target tissue to a temperature of about 40-45 C. for a specified period of time, thus stimulating fibroblasts to produce type 1 collagen preferably without producing significant amounts of type 3 collagen. The device includes a temperature sensor and a control circuit to maintain the desired temperature of the target tissue and avoid overheating. Target tissue includes tissue in and around the urethra, and in and around the anus including the perineum. The wand to which the RF grid array is mounted has visible gradations on it so that the user can treat one area at a time, then reliably move the grid array to the next adjacent area even though the grid array is hidden from view inside a portion of the body. The device can also be used for vaginoplasty.

The present invention relates to an apparatus for treating a sexual dysfunctional female patient. In the apparatus, there is provided at least one implantable stimulation for stimulating at least part of the sexually responsive tissue of the vulva or the wall or the vagina of the patient by movement of the stimulation device and contact between the stimulation device and at least one area of the sexually responsive tissue of the vulva or the wall of the vagina. There is further provided an energy-transforming device, a control unit for controlling the stimulation device and an energy storage device for receiving energy from the energy-transforming device. The control unit is further configured to determine a current state of the energy storage device.

Systems and methods for applying stimulating current to a patient for treating insufficient uterine contractions are provided. The system includes stimulation electrodes of a balloon electrode array device, a ring electrode array device, an electrode probe device, or a mesh electrode array device. Some aspects of the invention also provide a connector and cable device for coupling the stimulation electrodes to electronics for generating and providing the stimulating current to the stimulation electrodes.

Systems and methods for applying stimulating current to a patient for treating insufficient uterine contractions are provided. The system includes stimulation electrodes of a balloon electrode array device, a ring electrode array device, an electrode probe device, or a mesh electrode array device. Some aspects of the invention also provide a connector and cable device for coupling the stimulation electrodes to electronics for generating and providing the stimulating current to the stimulation electrodes.

A dynamic electroporation appliance comprises an oblong isolating applicator (1) with a rounded front part (4) and with two annular electrodes (3) arranged on its front surface at the sides of an intermediate opening (2). The intermediate opening it linked to at least one duct (9) associated with a central seat for a syringe (6) for dispensing pharmacological or aesthetic products or active ingredients. The electrodes (3) are energizable to produce a dynamic electroporation effect on the treated surface.

In one aspect, a neuromodulation device is described herein. In some embodiments, a neuromodulation device comprises a chamber operable to receive a nerve, at least one electrode disposed in the chamber, and a channel defined by two walls. In some embodiments, the channel of the device is in fluid communication with an interior of the chamber and an external surface of the device. In another aspect, methods of neuromodulation are described herein. In some embodiments, methods described herein can use one or more neuromodulation devices described herein.

The present invention provides a circuit module for pelvic floor muscle rehabilitation device and pelvic floor muscle rehabilitation device. The circuit module includes a first controller, a wireless communication module, an electromyographic signal collection module and a discharge module. The pelvic floor muscle rehabilitation device includes the circuit module. The pelvic floor muscle rehabilitation device is connected to a terminal device through the wireless communication module, and sends command signals to the first controller. Users can check the electromyographic signal collection results and control the intensity of electrical stimulation through the terminal device.

In one aspect, a neuromodulation device is described herein. In some embodiments, a neuromodulation device comprises a chamber operable to receive a nerve, at least one electrode disposed in the chamber, and a channel defined by two walls. In some embodiments, the channel of the device is in fluid communication with an interior of the chamber and an external surface of the device. In another aspect, methods of neuromodulation are described herein. In some embodiments, methods described herein can use one or more neuromodulation devices described herein.