Patent classifications
A61N1/0534
System and method for determination of connected neurostimulation leads
The types of electrode leads that are connected to an implantable medical device are determined based on electrical parameters that are measured at the electrodes that are positioned on the leads. The different types of known electrode leads have different physical electrode arrangements that impact the measured electrical parameters. Properties in the measured electrical parameters that are indicative of the physical arrangements of electrodes of known types of electrode leads are utilized to determine the types of leads that are connected to the implantable medical device.
Brain stimulation and sensing
- Evan D. Schnell ,
- Scott R. Stanslaski ,
- Ilan D. Gordon ,
- Steven M. Goetz ,
- Hijaz M. Haris ,
- Eric J. Panken ,
- Timothy R. Abraham ,
- Thomas L. Chouinard ,
- Susan Heilman Kilbane ,
- Karan Chitkara ,
- Christopher M. Arnett ,
- Alicia W. Thompson ,
- Kevin C. Johnson ,
- Ankush Thakur ,
- Lukas Valine ,
- Christopher L. Pulliam ,
- Brady N. Fetting ,
- Rucha Gokul G. Samant ,
- Andrew H. Houchins ,
- Caleb C. Zarns
Devices, systems, and techniques are disclosed for managing electrical stimulation therapy and/or sensing of physiological signals such as brain signals. For example, a system may assist a clinician in identifying one or more electrode combinations for sensing a brain signal. In another example, a user interface may display brain signal information and values of a stimulation parameter at least partially defining electrical stimulation delivered to a patient when the brain signal information was sensed.
Calibration of Stimulation Circuitry in an Implantable Stimulator Device Using Sensed Neural Responses to Stimulation
Methods and circuitry for calibrating stimulation circuitry in an implantable stimulator device (ISD) is disclosed. The ISD can sense neural response to the stimulation, and use an algorithm to assess those responses and determine a therapeutic window for a particular stimulation parameter, such as amplitude. Stimulation circuitry in the ISD is programmed with information indicative of the determined therapeutic window, such as by programming a minimum and/or maximum current amplitude. As well as restricting operation of the stimulation circuitry to within the therapeutic amplitude window, such programming calibrates the stimulation circuitry and allows an expanded range of, or all of, amplitude values supported by the stimulation circuitry to be used, which allows the amplitude to be incremented in smaller current increments.
Using Evoked Potentials for Brain Stimulation Therapies
Methods and systems for providing stimulation to a patient's brain using one or more electrode leads implanted in the patient's brain are described. The methods and systems help a clinician determine locations upon the lead where stimulation is expected to provide the best therapeutic benefit and the least side effects. Different locations upon the lead are used to provide stimulation and for each stimulation location evoked potentials are recorded. The evoked potentials are associated with likely beneficial therapeutic stimulation. Signals indicative of unwanted motor activity in the patient are also recorded for each of the stimulation locations. The recorded evoked potential signals and motor signals are used to determine stimulation locations that provide therapeutic benefit with minimal side effects. They can also be used to determine therapeutic windows for the potential stimulation locations.
SURFACE AND SUBSURFACE ELECTRODES FOR GUIDING STIMULATION ELECTRIC CURRENTS WITH ELECTRIC FIELDS FOR COCHLEA IMPLANTED ELECTRODES
We disclose the use of passive, or field-shaping electrodes, below the surface of the supporting structure of a cochlear implant. The location of the field-shaping electrodes below the surface of the supporting structure, allows for the use of the field-shaping electrodes to exist in the structure without decreasing the available space for the active, stimulating electrodes at the surface. The field-shaping electrodes are to direct the electric currents injected by the stimulating (active) electrodes onto the one-and-only-one neuron that is expected, by the brain, to receive vibrations from one-and-only-one frequency. The objective of the field-shaping electrodes is to prevent, or, at least to decrease, the leaking of the stimulating current from any stimulating active electrode onto any neuron other than the neuron that is directly in front of the electrode in question, which is the only neuron that is expected to receive excitation for that frequency associated with each electrode.
OPTICAL STIMULATION SYSTEM WITH ON-DEMAND MONITORING AND METHODS OF MAKING AND USING
An optical stimulation system includes a light source configured to produce light for optical stimulation; a light monitor; an optical lead coupled, or coupleable, to the light source and the light monitor; and a control module coupled, or coupleable, to the light source and the light monitor. The control module includes a memory, and a processor coupled to the memory and configured for receiving a request for verification or measurement of a light output value; in response to the request, receiving, from the light monitor, a measurement of light generated by the light source; and, based on the measurement, reporting a response to the request.
MEDICAL DEVICE LEAD TIP ANCHOR
Systems and methods which provide retractable anchor configurations for medical device leads are described. A retractable anchor may implement a retractable distention composed of a resilient material. The retractable distention may be distended when in a neutral state and may be contracted when in a biased state. A biasing bulkhead may be configured to receive a bias force sufficient to retract the retractable distention. A stylet may be inserted into an axial lumen of a medical device lead having retractable tip anchor structure and may engage the biasing bulkhead to apply a bias force. A stylet knob may be configured to interface with the stylet and provide bias force to be transferred to the biasing bulkhead of the retractable tip anchor structure. Locking the stylet knob on the medical device lead may maintain the bias force applied to the biasing bulkhead until the stylet knob is unlocked.
Systems, methods and media for detecting and facilitating an effortful mental task by providing real-time deep brain stimulation
In accordance with some embodiments of the disclosed subject matter, mechanisms (which can, for example, include systems, methods, and media) for detecting an effortful mental state providing real-time deep brain stimulation to enhance performance of effortful mental tasks are provided. In some embodiments, system for detecting and facilitating effortful mental states is provided, the system comprising: monitoring sensors to capture neural activity from a subject's brain; an implanted stimulator to provide electrical stimulation to the subject's brain; a hardware processor programmed to: correlate activity in a first and second region of the subject brain during task performance; correlate activity in the first and second regions during task non performance; train a support vector machine (SVM) using the correlations as first and second class examples; and provide stimulation to augment brain function when the SVM indicates, based on activity in the first and second regions, the subject is in the mental state.
Device and means to ameliorate discomfort and pain during visual inspections of inner body parts and similar procedures
A device and means to decrease the pain associated with colonoscopy and similar procedures to examine the oesophagus, the stomach, etc. The device uses electrical currents of both positive and negative polarity, or alternating current. The improvement described can be incorporated into existing bodies of existing devices. Application on colonoscopy screenings and intestine polyp collection and other types of biopsies.
Methods and systems for optimizing therapy using stimulation mimicking natural seizures
Systems, methods, and devices for automatic generation of a stimulation therapy that mimics electrographic activity in the brain at natural seizure termination define a stimulation therapy to be generated by an implanted component of a medical device system and delivered to a subject through identifying data characterizing a patient's seizures, especially at termination. A machine learning model identifies the seizures or seizure types from which to establish a canonical seizure or seizure type, and an algorithm translates the canonical seizure or seizure type into data that can be used to characterize a stimulation therapy. The systems, methods, and devices, include those configured to deliver the stimulation therapy that emulates the canonical seizure or seizure type when the seizure is detected, with the aim of terminating the seizure sooner than it would terminate without intervention.