A61K2236/30

Cannabis Parthenogenesis Practical Resin And Fiber Cultivation Ptocess
20240269207 · 2024-08-15 ·

The term medical cannabis and medical marijuana existed long before any codifying of law. They were around before industry began and the words actually had meaning. Medical cannabis means sensimilla, and sensimilla is a latin word meaning without seed. The reason sensimilla is preferred for medicine is simple. Cannabis plants are highly photo-sensitive. This means the plant's entire life cycle must be controlled with light to efficiently and effectively produce medicine. When done properly you will have a vegetative photo-period and a flower photo-period, each being different in duration, intensity, and color of lighting. Working like this allows you to keep a mother plant theoretically indefinitely. This allows you to increase plant potency over time and gives you a source for clones. Clones can be developed directly beside the mother until ready to flower. Establishing a mother plant and taking clones allows for a few things. First, you now have a reliable source of female cannabis plants and no seeds are required to be germinated. Second, potency goes up the longer the mother is in the vegetative state. Third, if there are any abnormalities it is easy to spot. Training yourself to cultivate in this manner will make it really easy to identify when somethings wrong, and with cannabis something wrong can turn catastrophic quickly. When the female clone has matured and is ready for flowering they are moved away from the mother. They are provided with a different color of light, as well as duration of light and nutrients. When a cannabis plant is flowering in this manner and no male plants are present, and no pollination occurs, it is now in prime condition to provide our medicine, in the form of its resin. In nature, the resin is what the plant uses to entice pollination. If unpollinated, a cannabis plant will freely flow its resin until harvest. If pollinated, it begins to shut down resin flow because it no longer needs to be pollinated. This is when the plant begins to put its energy into seed production and inhibits our medicine. It is particularly this reason why it is imperative for medical cannabis to meet the standard of sensimilla.

SMALL MOLECULE MODULATOR TARGETING A RARE HISTONE MODIFICATION REGULATING ADIPOGENESIS AND PHARMACEUTICAL FORMULATION THEREOF

The present invention relates to substituted benzophenones of structural Formula I employed as small molecule inhibitor for controlling obesity. The present invention further relates to screening of small molecule inhibitors against p300 which selectively targets histone butyrylation thereby specifically inhibiting adipogenesis further aiding to prevention of weight gain. The present invention reveals that histone butyrylation increases during adipogenesis. Hence, inhibition of histone butyrylation by a small molecule inhibitor would be a promising therapeutic strategy to control obesity. Significantly, besides inhibiting adipogenesis in cellular model, it also prevents weight gain in high fat diet based mouse model system, indicating the possible use of the scaffold for obesity control.

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METHODS FOR IMPROVING BONE QUALITY AND PROMOTING CARTILAGE DIFFERENTIATION BY CHRYSOPHYLLUM CAINITO EXTRACT AND MANUFACTURING METHOD THEREOF
20240261354 · 2024-08-08 ·

Methods for improving bone quality and promoting cartilage differentiation in a subject in need thereof are provided. The methods include: administering to the subject an effective amount of Chrysophyllum cainito extract. The Chrysophyllum cainito extract is obtained by extracting early-harvested fruit of Chrysophyllum cainito by a cellulase complex solution. The cellulase complex solution is prepared by adding 0.1% of cellulase complex in water. The Chrysophyllum cainito extract has at least one of the following effects of: promoting to production of osteocalcin by osteoblasts, promoting osteocalcin content in blood, improving bone density of lumbar vertebra, and promoting secretion of glycosaminoglycans by chondrocytes.

Cosmetic use of an extract of balanites almonds to improve hair strength

The invention concerns the use of a cosmetic compound to improve hair strength, said cosmetic compound comprising as an active ingredient an extract of Balanites almonds.

COMPOSITIONS AND METHODS COMPRISING YEAST ORGANISMS AND EXTRACTS THEREOF
20180318207 · 2018-11-08 ·

Disclosed herein are methods and compositions comprising whole yeast organisms and/or lipid yeast extract. Such compositions may be cosmetic, medical, biotechnological or agricultural compositions, comprising one or more cosmetic, medical, biotechnological or agricultural ingredients. The invention comprises methods of making such compositions. The yeast components of the compositions may be derived from yeast cultures which comprise at least 0.1% oil by dry weight.

Water-soluble granular material for producing a drinking soltuion

The invention relates to water-soluble granules for preparing a drinkable solution, in particular for preventing or treating symptoms associated with mild to moderate chronic venous insufficiency of the lower extremities, containing at least 20 percent by weight of a concentrated extract of red wine leaves, and to a ready-to-use packaging unit comprising one or more portion sachets which contain the granules according to the invention.

Method for removing contaminants from cannabinoid distillates

A method for removing contaminants such as pesticides and fungicides from cannabinoid extracts. Cannabinoid extracts containing contaminants may be dissolved in a water and ethanol solution, and then cooled to allow water-soluble contaminants to settle out of the mixture. The water and ethanol may then be removed via evaporation or distillation, leaving purified cannabinoids without contaminants. Contaminant removal may be incorporated into a method for producing a blended extract of cannabinoids and terpenes, which extracts terpenes using supercritical CO2, and extracts a cannabinoid concentrate from the residual material using a cold ethanol flush followed by distillation and then by contaminant removal; the CO2-extracted terpenes are then added back to the purified cannabinoid concentrate in a final blending step. Blending terpenes at the end of extraction may enhance the flavor and effectiveness of the purified cannabinoid concentrate.

Nutriprotective diet

The present document describes a nutriprotective diet comprising a nutriprotective amount of a sugar plant syrup, a sugar plant syrup extract, a sugar plant extract, or combinations thereof The present document also describes a method of eliciting a nutriprotective effect in a subject, which comprises administering a nutriprotective amount of a nutriprotective diet according to the present invention. Also, the present document also describes a method of treating a subject with a disorder, by administering a nutriprotective amount of a nutriprotective diet according to the present invention. Also, the present document describes a process for the extraction of polyphenolic compounds from maple syrup using adsorbent materials, and the extracts obtained therefrom.

VACUUM DISTILLATION FOR ENRICHING CANNABIDIOL
20180282250 · 2018-10-04 ·

The present invention relates to a method for producing, obtaining and enriching cannabidiol (CBD) and to the use thereof. The invention also relates to a cannabidiol extract and the use of an obtained cannabidiol extract in the pharmaceutical and cosmetic fields.

COMPOSITION FOR PREVENTING ALOPECIA OR STIMULATING HAIR GROWTH CONTAINING EXTRACELLULAR POLYSACCHARIDE PRODUCED FROM CERIPORIA LACERATA AS ACTIVE INGREDIENT
20180280457 · 2018-10-04 · ·

The present invention relates to extracellular polysaccharide produced from Ceriporia lacerata, a mycelium culture medium of Ceriporia lacerata containing the extracellular polysaccharide, and a composition for preventing alopecia or stimulating hair growth containing dry powder or an extract of the mycelium culture medium as an active ingredient. The composition according to the present invention inhibits expression of TGF- and is thus superb in preventing alopecia or stimulating hair growth and a composition containing said composition can be effectively used as a pharmaceutical composition, quasi-drug, healthy functional food and cosmetic composition for preventing alopecia or stimulating hair growth.