An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

A device for therapeutic neuromodulation in a nasal region can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

The present disclosure relates to an ablation device, which relates to the technical field of cryoablation treatments, and is used for solving the technical problem of an excessive burden on an operator caused by the volume of a delivery device being too large. The ablation device of the disclosure comprises an ablation needle and a working medium transmission device connected to the ablation needle. The working medium transmission device comprises a first delivery tube and a second delivery tube. The first delivery tube and the second delivery tube are configured to be of split structures that are independent of each other, such that the structure of the working medium delivery device at the rear end of the ablation needle is smaller and lighter, and thus the burden on the operator's operation can be reduced, making the operation to be more flexible and convenient.

A left atrial appendage (LAA) occluder and an occluding system are provided. The LAA occluder includes a sealing portion and an ablation portion arranged in the sealing portion, as well as a hollow proximal connector at a proximal end of the sealing portion. The ablation portion is connected to the proximal connector. The ablation portion is used to freeze an LAA after being injected with cryogen so as to form an annular isolation band on an inner wall of the LAA for blocking the conduction of electrical signals between the LAA and a left atrium.

Cryogenic devices and methods of using and manufacturing cryogenic devices are disclosed. An exemplary cryogenic device may include an enclosed distal tip delineating a cavity in fluid communication with an egress orifice and an ingress orifice, where at least a portion of an exterior of the distal tip comprises a thermal application zone; an exhaust conduit in fluid communication with the egress orifice; a supply conduit in fluid communication with the ingress orifice, the supply conduit helically extending around at least a portion of the exhaust conduit; and/or a deformable wrap at least partially circumscribing the supply conduit and leaving exposed the thermal application zone.

Cryogenic probes and related methods are disclosed. An example cryogenic probe may include a distal ablation tip and an elongated, generally tubular shaft extending proximally from the ablation tip. The shaft may include a flexible thermoplastic body, a supply conduit extending through the body, and/or an exhaust conduit extending through the body. At least one of the supply conduit and the exhaust conduit may be embedded within the body.

A device for providing a cryotherapy ablation treatment includes a piping assembly and a snow horn adapted to create a spray of snow from a pressurized source of a low-temperature liquid, a tubular applicator for collecting a mass of snow at a prescribed density that is sufficient to allow the mass to serve as the needed, low temperature, thermal reservoir for the device after the applicator's distal end has been disconnected from the snow horn end so that it can to be used during the treatment process, and an applicator tip adapted to allow it to connect to the applicator's distal end and be used to treat those specific locations which are to receive this treatment.

A method using a guide to assist in insertion of a helicoidal member in a target biological tissue. The method includes abutting a substantially longitudinally extending portion of the guide against a target tissue exposed surface with the helicoidal member mounted thereto so that at least a portion of the guide is inserted in a helicoidal member passageway substantially parallel to a helicoidal member longitudinal axis of the helicoidal member; adhering the substantially longitudinally extending portion of the guide to the target tissue exposed surface with the helicoidal member longitudinal axis substantially parallel to the target tissue exposed surface; and advancing the helicoidal member in the target biological tissue in a substantially helicoidal movement with the guide remaining substantially fixed relative to the target biological tissue.

An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

Embodiments described herein are directed to methods of treating visceral fat where the method includes the steps of identifying visceral fat to be treated, inserting a laparoscopic device into the visceral fat to be treated, inserting a treatment instrument into the laparoscopic device such that a distal treatment section of the treatment device is delivered into the visceral fat, cooling the distal treatment section and the visceral fat adjacent to the distal treatment section to a cooling temperature no colder than approximately −20° C., and wanning the distal treatment section and the visceral fat adjacent to the distal treatment section to a temperature greater than the cooling temperature.