Disclosed is an intraluminal imaging system that includes an intraluminal imaging catheter or guidewire configured to obtain imaging data associated with a lumen of a patient while positioned within the lumen, and a processor in communication with the intraluminal imaging catheter or guidewire. The processor is configured to generate aplurality of image frames using on the imaging data, automatically measure an anatomical feature in the image frames, identify a target frame representative of a region of interest, identify a proximal reference frame located proximal of the target frame, and identify a distal reference frame located distal of the target frame. The processor is also configured to output a single screen display including the proximal reference frame, target frame, distal reference frame, and a longitudinal representation of the lumen showing the respective positions of the proximal refernce frame, the target frame, and the distal refernce frame.

Various embodiments are described herein for a system and associated method for performing collagen assessment of an object using Photoacoustic Image (PA) data obtained for the object, wherein the method is performed by a processing unit and the method comprises: obtaining beamformed PA image data for the object using at least three wavelengths related to chromophores including collagen, oxyhemoglobin and deoxyhemoglobin, the three wavelengths being less than 1000 nm; performing spectral decomposition on the beamformed PA image data using the three wavelengths to obtain data that is used for generating at least one collagen map; and determining a collagen score for the at least one collagen map.

The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.

An apparatus comprising an array of polymer-based capacitive micromachined ultrasonic transducers positioned on a substrate. The substrate may be at least substantially transparent to ionizing radiation, be flexible, and/or have walls positioned thereon to protect the transducers.

Arrangements and methods are provided for obtaining information associated with an anatomical sample. For example, at least one first electro-magnetic radiation can be provided to the anatomical sample so as to generate at least one acoustic wave in the anatomical sample. At least one second electro-magnetic radiation can be produced based on the acoustic wave. At least one portion of at least one second electro-magnetic radiation can be provided so as to determine information associated with at least one portion of the anatomical sample. In addition, the information based on data associated with the second electro-magnetic radiation can be analyzed. The first electro-magnetic radiation may include at least one first magnitude and at least one first frequency. The second electro-magnetic radiation can include at least one second magnitude and at least one second frequency. The data may relate to a first difference between the first and second magnitudes and/or a second difference between the first and second frequencies. The second difference may be approximately between −100 GHz and 100 GHz, excluding zero.

A fractionated photoacoustic flow cytometry (PAFC) system and methods for the in vivo detection of target objects in biofluidic systems (e.g., blood, lymph, urine, or cerebrospinal fluid) of a living organism is described. The fractionated system includes a fractionated laser system, a fractionated optical system, a fractionated acoustic system, and combinations thereof. The fractionated laser system includes at least one laser or laser array for pulsing a target object within the circulatory vessel with fractionated focused laser beams. The fractionated optical system separates one or several laser beams into multiple beams in a spatial configuration on the skin above the circulatory vessel of the living organism. The fractionated acoustic system includes multiple focused ultrasound transducers for receiving photoacoustic signals emitted by the target object in response to the fractionated laser beams. The target objects have intrinsic photoacoustic contrast or may be labeled with photoswitchable or spaser-based probes. Fractioned beams may be used also for diagnostics with other spectroscopic methods (e.g., fluorescence, Raman or scattering) and energy sources both coherent and conventional such as lamp and LED in the broad spectral range from 10 Å to 1 cm (e.g., X-ray, UV, visible, NIR or microwaves) in continuous wave and pulse modes.

An object information obtaining device includes a light source which emits light, an acoustic wave detecting unit which detects a photoacoustic wave generated by irradiation of an object with the light, and outputs an electric signal in response to detection of the photoacoustic wave, and a processing unit configured to perform two or more types of processing to photoacoustic signal data based on the electric signal to obtain object information corresponding to each of the two or more types of processing, and to display on a display unit the object information corresponding to at least one processing selected by a user out of the two or more types of processing.

A subject information acquisition apparatus comprises a casing in which a transmissive member capable of transmitting acoustic waves and laser beams therethrough is provided; a light irradiating unit disposed inside the casing so as to irradiate a subject with laser beams with the transmissive member interposed; an acoustic wave probe disposed inside the casing so as to receive acoustic waves with the transmissive member interposed; and a scanning mechanism disposed inside the casing so as to move the light irradiating unit and the acoustic wave probe in relation to the casing, wherein the casing is configured to be movable on the subject.

The present invention provides a breast computed tomography system in which the body motion and the pain of an examinee during capturing of images of the breast are reduced. The breast computed tomography system includes a gantry accommodating a light emitting unit that radiates light onto the breast. The gantry includes a gripper having a right gripping portion and a left gripping portion.

an object information acquiring apparatus comprises a light emission unit configured to emit light beams from a plurality of emission positions; a conversion unit configured to convert acoustic waves generated when an object is irradiated with the light beams emitted by the light emission unit into electric signals; a beam profile acquisition unit configured to acquire information relating to beam profiles of the light beams emitted by the light emission unit, the beam profiles corresponding respectively to the plurality of emission positions; and a characteristic information acquisition unit configured to acquire characteristic information of the object on the basis of the information relating to the beam profiles corresponding to the plurality of emission positions and the electric signals.