The invention relates to a method for controlling a laser (12) of a treatment apparatus (10), comprising the steps of: generating a plurality of laser pulses (34) with a predefined energy below a photodisruption regime of a polymer material (26), irradiating the area (16) with the laser pulses (34), wherein a refractive index of the polymer material (26) changes at the irradiated irradiation point (36) depending thereon, generating a first irradiation line (38) in a first depth plane (40), wherein the first depth plane (40) is formed substantially perpendicularly to an optical axis (20) of the area (16), generating a second irradiation line (42) in a second depth plane (44) different from the first depth plane (40), wherein the first depth plane (40) and the second depth plane (44) overlap at least in certain areas viewed in the direction of the optical axis (20) and the second depth plane (44) is formed substantially perpendicularly to the optical axis (20). Further, the invention relates to a treatment apparatus (10), to a computer program, to a computer-readable medium as well as to a surgical method.

In a laser cataract procedure that also corrects for astigmatism, an iris registration method compares an iris image of a patient's eye taken when the eye is not docked to a patient interface device with an iris image of the same eye that is docked to the patient interface, to calculate a rotation angle between the two images. The astigmatism axis of the eye is measured when the eye is not docked, and the measured axis is rotated by the calculated rotation angle to obtain a rotated astigmatism axis relative to the iris image of the docked eye. The laser cataract procedure is performed based on the rotated astigmatism axis. The rotation angle is calculated by optimizing a transformation that transforms the undocked iris image to match the docked iris image, where the transformation includes a dilation factor that accounts for different pupil dilation of the two iris images.

Refractive index writing system and methods employing a pulsed laser source for providing a pulsed laser output at a first wavelength; an objective lens for focusing the pulsed laser output to a focal spot in an optical material; a scanner for relatively moving the focal spot with respect to the optical material at a relative speed and direction along a scan region for writing one or more traces in the optical material defined by a change in refractive index; and a controller for controlling laser exposures along the one or more traces in accordance with a calibration function for the optical material to achieve a desired refractive index profile in the optical material. The refractive index writing system may be for writing traces in in vivo optical tissue, and the controller may be configured with a calibration function obtained by calibrating refractive index change induced in enucleated ocular globes. A real-time process control monitor for detecting emissions from the optical material transmitted through the objective lens at a second wavelength may further be employed while writing the one or more traces.

Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incisions to form a top lenticular incision, a bottom lenticular incision of a lens in the subject's eye, an added shape between the top and bottom incisions where the added shape has no corrective power and a transition ring bisecting both the top and bottom lenticular incisions.

Embodiments generally relate to systems and methods for lenticular laser incisions based on wavefront maps. In an embodiment, a method comprises obtaining a wavefront map of a free eye using wavefront aberrometry to measure a refractive error, obtaining an iris image for the free eye using wavefront aberrometry, determining a free eye cutting profile to cut the cornea based on the wavefront measurement, determining a first translation of the free eye cutting profile based on estimated perturbation of the eye with a docking patient interface, docking the eye to a patient interface of an ultrashort pulsed laser system, obtaining an iris image for the docked eye, determining a second translation of the cutting profile for the docked eye from the free eye, using comparisons between the two iris images, and incising a bottom surface incision in the cornea based on the two translated cutting profiles.

A device for producing control data for a laser device for the surgical correction of defective vision. The device produces the control data such that the laser emits the laser radiation such that a volume in the cornea is isolated. The device calculates a radius of curvature R.sub.CV* to determine the control data, the cornea reduced by the volume having the radius of curvature R.sub.CV* and the radius of curvature being site-specific and satisfying the following equation: R.sub.CV*(r,φ)=1/((1/R.sub.CV(r,φ))+B.sub.COR(r,φ)/(n.sub.c−1))+F, wherein R.sub.CV(r,φ) is the local radius of curvature of the cornea before the volume is removed, n.sub.c is the refractive index of the material of the cornea, F is a coefficient, and B.sub.COR(r,φ) is the local change in refractive force required for the desired correction of defective vision in a plane lying in the vertex of the cornea, and at least two radii r1 and r2 satisfy the equation B.sub.COR(r=r1,φ)≠B.sub.COR(r=r2,φ).

Disclosed is an ophthalmological treatment apparatus for modifying a shape of a corneal surface of a human eye. The apparatus includes a surgical laser device for implementing tissue cuts. The apparatus further includes a computerized control device in operative coupling with the surgical laser device, the control device being designed to control the laser device to implement tissue cuts according to a cut geometry with a primary tissue cut and a secondary tissue cut, wherein the primary tissue cut is a relief cut and extends into the depth of the conical eye tissue, and wherein the secondary tissue cut lies within the conical eye tissue, such that the secondary tissue cut adds to the relieving effect of the primary tissue cut.

Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in the subject's eye, where each of the top and bottom lenticular incision includes a center concave portion and an edge transition portion that has a smooth convex shape and is smoothly joined to the center concave portion.

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method for vergence matching includes calculating vergence of a wave after refraction on a surface of an IOL and, based on an estimated curvature, converting an initial phase map into a vergence-matched phase map, such that the initial phase map follows the curved vergence of the wavefront.

A method of corneal implantation with cross-linking is disclosed herein. In one or more embodiments, the method includes the steps of: (i) prior to implantation, treating an implant formed from donor corneal tissue or a tissue culture grown corneal stroma with a solution of sodium dodecyl sulfate (SDS), Triton X-100, benzalkonium chloride (BAK), Igepal, genipin, 100% glycerol, or alcohol for making the implant acellular, and for killing any bacteria, viruses, or parasites prior to implantation; (ii) implanting the implant into a recipient cornea; (iii) applying laser energy to the implant so as to modify the refractive power of the implant while being monitored using a Shack-Hartmann wavefront system so as to achieve a desired refractive power for the implant; and (iv) applying a cross-linking solution and irradiating the implant to cross-link the implant to prevent an immune response to the implant and/or rejection of the implant by a patient.