A mixing vial having a hollow interior chamber with a tubular portion having distal and proximal open ends and a stopper positioned in sealing relationship in the tubular portion, the stopper having a hollow interior chamber with an open end and a dislodgeable plug positioned in and sealing the open end.

Disclosed is a combination of an infusion set consisting of infusion tubing and needle connected to a drug cartridge, the latter comprising a cylindrical body of inner diameter and having an open rear end, wherein a stopper is slidably disposed within the body. In an initial state after the cartridge has been filled, the stopper is partially disposed within the body such that the stopper protrudes from the rear end of the body by a distance. Pushing the stopper into the cartridge by said distance, i.e. until the stopper is flush with the rear end, displaces a predetermined volume according to E, B and the cylindrical geometry of the cartridge, which is large enough to effect complete air priming of the cartridge, infusion tubing and infusion needle.

A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. The reservoir is suitable for mixing a topical formulation of multiple constituents using an electronic mortar and pestle and is closed using the applicator cap. Alternatively, the reservoir may be prefilled with a ready-to-use cream and medicament formulation, then sealed with a removable seal. The topical applicator can also include a one-way ratcheting feature to prevent reverse movement (repel) of the metered dosing system. Metered doses can be dispensed through holes in the applicator cap by rotating a knob, which has detent positions that correspond to discrete doses, and which provides audible and tactile feedback.

A method for buffering anesthetic.

Dual vial adapter assemblages having a triple component construction as follows: a first vented female vial adapter for telescopic mounting on a drug vial, a second vented female vial adapter for telescopic mounting on a liquid vial and a tubular liquid transfer coupler for coupling the first vented female vial adapter and the second vented female vial adapter for establishing a dual sealed lumen arrangement therebetween. The dual sealed lumen arrangement includes a central sealed liquid lumen for gravitational flow of liquid contents from a liquid vial to a drug vial and a sealed air lumen radial outward from the central sealed liquid lumen for venting air displaced from the drug vial to the liquid vial for assisting the gravitational flow of liquid contents by creating a closed system between the liquid vial and the drug vial.

A bag having two accesses, an inlet and an outlet, both containing closing devices for releasing or stopping the flow of a liquid that flows into or out of the bag. The inlet has a filtering element for retaining particles possibly produced by the coring phenomenon which can occur when the spike of the inlet ruptures the plug of the bottle. Also provided is a safety device used for permanently attaching the bottle to the inlet.

A mixing vial having a hollow interior chamber with a tubular portion having distal and proximal open ends and a stopper positioned in sealing relationship in the tubular portion, the stopper having a hollow interior chamber with an open end and a dislodgeable plug positioned in and sealing the open end.

A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. The reservoir is suitable for mixing a topical formulation of multiple constituents using an electronic mortar and pestle and is closed using the applicator cap. Alternatively, the reservoir may be prefilled with a ready-to-use cream and medicament formulation, then sealed with a removable seal. The topical applicator can include a fast purge feature that overrides the metered dosing system to facilitate removal of air from the reservoir. The topical applicator can also include a one-way ratcheting feature to prevent reverse movement (repel) of the metered dosing system. Metered doses can be dispensed through holes in the applicator cap by rotating a knob, which has detent positions that correspond to discrete doses, and which provides audible and tactile feedback.

The present invention relates to a device for vacuum and vent tube stoppering a medical container. The device includes a main body defining an internal volume that has a first variable pressure chamber configured to be connected to a vacuum pump, the main body being configured to receive the proximal end of a medical container so that said medical container is in communication with the first variable pressure chamber. A vent device including a vent tube is moveable inside the internal volume of the main body along a longitudinal axis between a proximal rest position and a distal operative position. A piston rod is moveable inside the internal volume of the vent tube along the longitudinal axis between a proximal rest position and a distal operative position. A container holder system is provided in the main body, in communication with the first variable pressure chamber.

A mixing vial having a hollow interior chamber with a tubular portion having distal and proximal open ends and a stopper positioned in sealing relationship in the tubular portion, the stopper having a hollow interior chamber with an open end and a dislodgeable plug positioned in and sealing the open end.