Provided are methods for preventing, ameliorating, or treating a skin disorder, disease, or condition with a casein kinase 1 inhibitor. Also provided are methods of increasing skin pigmentation or sunburn protection by inhibiting casein kinase 1.

Provided is a variant strain of the genus Yarrowia. More specifically, provided are a variant strain of the genus Yarrowia, in which activity of phosphatidylethanolamine N-methyltransferase (PEMT) or phospholipid methyltransferase is inactivated, and a method of increasing a fat in the strain, including culturing the strain, or a method of preparing a fat.

A method of treating a person's skin is disclosed. The method can include topically applying to the skin a composition comprising jojoba oil and an oil extract of Opuntia ficus-indica tuna or Opuntia ficus-indica nopales, or a combination thereof, to treat the person's skin.

A method for reducing a presence of sebum on skin, reducing an appearance of shiny skin, or reducing an appearance of the size of skin pores is disclosed. The method can include topically applying to skin a composition comprising a navy bean extract comprising amino acids, an extract of Bambusa vulgaris wendl shoots, and charcoal.

A method for treating a person's skin is disclosed. The method includes topically applying to the skin a composition comprising from 0.001% to 20% by weight of an aqueous, alcoholic, or aqueous-alcoholic extract from a plant extract.

The present invention relates generally to methods and compositions useful for improving skin barrier function and reducing skin redness. The compositions comprise cholesterol, ceramide II, and shea butter or cholesterol, ceramide II, shea butter, saccharide isomerate, hydroxyphenyl propamidobenzoic acid, and Phoenix dactylifera (date palm) seed extract.

Disclosed herein is a composition for enhancing skin elasticity or improving skin wrinkles. In one aspect, 2-isopropylmalic acid or a salt, hydrate or solvate thereof, which is an active ingredient of the present disclosure, activates skin primary cilia and inhibits the expression of MMP-1 to enhance skin elasticity and improve skin wrinkles. In addition, in one aspect, 2-isopropylmalic acid or a salt, hydrate or solvate thereof, which is an active ingredient of the present disclosure, is a safe material and has the advantage that it can be treated in the living body in various forms such as cosmetics and food.

The present invention relates to a composition comprising arginine aspartate. The composition according to the present invention not only reduces 2-nonenal, but also inhibits the expression of MMP-1, has a collagen synthesis ability, reduces the expression of TNF-α, and inhibits the activity of tyrosinase. Therefore, the composition according to the present invention can be effectively used for suppressing senile body odor, alleviating wrinkles, anti-inflammation or whitening.

The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor.

Methods and compositions for stimulating hair growth are disclosed. Compositions for stimulating hair growth include two or more of hyaluronic acid, osteopontin, and another CD44 binding ligand. Methods for stimulating hair growth include administering such composition into the skin of a patient.