The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

A single and dual component dental composite restorative featuring anti-microbial and low Coefficient of Thermal Expansion (CTE) compounds is disclosed. The exemplary anti-microbial compound is zinc oxide. The CTE of the dental composite restorative is the same as, or substantially similar, to that of dentin. By maintaining a CTE substantially similar to that of dentin, the Margin Percolation phenomenon is minimized, which decreases the incidence of secondary caries.

Disclosed are biomimetic mineral based endodontic cement compositions. An endodontic cement comprises a paste A and a paste B. The paste A comprises a pozzolanic cementitious mineral paste and the paste B is a mixture comprising polyanionic polymers, phosphates, cement setting modulators, host-inclusion particles, bioactive glasses, and radiopacity agents suspended in a liquid carrier.

The present invention provides a curable calcium phosphate composition for biological hard tissue repair that yields a cured product excellent in durability in a wet environment such as in a body or an oral cavity. The present invention relates to a curable calcium phosphate composition for biological hard tissue repair, including tetracalcium phosphate particles (A), calcium hydrogen phosphate particles (B), calcium carbonate particles (C), and water (D), the curable calcium phosphate composition including 5 to 75 parts by weight of the tetracalcium phosphate particles (A), 10 to 70 parts by weight of the calcium hydrogen phosphate particles (B), and 2 to 50 parts by weight of the calcium carbonate particles (C) per 100 parts by weight of the total of the tetracalcium phosphate particles (A), the calcium hydrogen phosphate particles (B), and the calcium carbonate particles (C).

The present application is directed to a dental material and a method of using the dental material. The dental material can include a hardenable resin; an initiator system; a filler; and from about 1 wt % to about 20 wt % zinc compound, based on the weight of the hardenable resin. The contrast ratio of the cured dental material increases by at least about 10 units after continuous exposure to an aqueous solution for 21 days

The present invention provides a dentinal tubule occlusion material excellent in terms of initial degree of dentinal tubule occlusion, resistance of dentinal tubule occlusion to acids, handling properties, and storage stability. The present invention relates to an one-pack type dentinal tubule occlusion material comprising fluorapatite particles (A) having an average particle diameter of 0.6 to 10 μm, inorganic particles (B) having an average particle diameter of 0.6 to 10 μm and reactive with water to form apatite, and a non-aqueous dispersant (C).

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

The present invention relates to a hydrogel formulation in which the solid phase is composed of a continuous net work of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants.