Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.

The invention relates to an extracorporeal blood treatment device comprising a hydraulic system II comprising a plurality of flow paths, the blood treatment device having a control unit 40 which provides an operating mode for disinfecting the hydraulic system with a liquid which can be supplied via one of the flow paths. Moreover, the invention relates to a method for operating an extracorporeal blood treatment device with a hydraulic system comprising a plurality of flow paths. The blood treatment device according to the invention is characterized in that the hydraulic system II has a valve device 23 which provides several switching positions. The valve device 23 has an inlet 25A for the liquid for disinfecting the hydraulic system and a plurality of outlets 26A, 27A, 28A, wherein in a switching position the inlet 25A is connected to one of the outlets 26A, 27A, 28A and in another switching position the inlet is connected to a plurality of outlets 26A, 27A, 28A. The inlet 25A of the valve device 23 is in fluid communication with the flow path via which liquid for disinfecting the hydraulic system II can be supplied, and the outlets 26A, 27A, 28A of the valve device 23 are in fluid communication with another flow path of the hydraulic system, so that liquid can simultaneously be supplied to the individual flow paths.

A medical fluid treatment system includes a source of purified water; at least one concentrate for mixing with the water from the source to form a treatment fluid; a disposable set including a pumping portion, a concentrate line in fluid communication with the concentrate source and the pumping portion, and a patient line in fluid communication with the pumping portion, the patient line including a filter having a membrane configured to filter the treatment fluid, the filter configured such that (i) fresh treatment fluid flowing from the pumping portion towards a patient flows through the membrane and (ii) used treatment fluid flowing through the filter from the patient to the pumping portion bypasses the membrane; and a medical fluid delivery machine including a pump actuator operable with the pumping portion of the disposable set.

A method of sanitizing liquid for use in a medical device, the method comprising the steps of providing a medical device defining a water circuit with a volume of liquid, sensing the temperature of the volume of liquid with a sensor, heating the volume of liquid from an initial temperature to exceed a threshold temperature, maintaining the volume of liquid above the threshold temperature, determining a time-temperature value for the volume of liquid periodically once the threshold temperature has been exceeded, calculating a cumulative time-temperature value and providing an output signal once the cumulative time-temperature value has reached a level indicative of a sanitizing dose. A medical device and a liquid sanitizer are also disclosed.

The present disclosure relates to a contact protection apparatus for covering connection point(s) of a medical fluid-conducting cassette used for a medical treatment. The contact protection apparatus includes at least one covering section for covering the connection point before the use of the cassette, and at least one connection section for detachably connecting the contact protection apparatus or for holding the contact protection apparatus on the cassette. It further relates to a medical fluid-conducting cassette with a contact protection apparatus.

An extracorporeal blood treatment device is provided that includes a hydraulic system having a plurality of flow paths. A control unit provides an operating mode for disinfecting the hydraulic system with a liquid supplied via one of the flow paths. A method for operating the extracorporeal blood treatment device is also provided. The hydraulic system has a valve device that provides several switching positions. The valve device has an inlet for a liquid for disinfecting the hydraulic system, and a plurality of outlets. In a first switching position, the inlet is connected to one of the outlets. In another switching position, the inlet is connected to a plurality of the outlets. The inlet of the valve device is in fluid communication with a first flow path and the outlets are in fluid communication with another flow path. Disinfecting liquid can simultaneously be supplied to the individual flow paths.

An inline heating system including an inline heater including a heater element; a control unit configured to cause one of voltage or current to be applied to power the inline heater; and a current or voltage meter positioned and arranged to measure the other of current or voltage at the heater element due to the applied voltage or current, wherein the control unit is further configured to determine a heater element resistance using the applied voltage or current and the measured current or voltage as part of a no flow or low flow condition detection algorithm implemented by the control unit, wherein the voltage or current applied to power the inline heater is stopped if the no flow or low flow condition is detected.

This disclosure relates to dialysis systems and methods. In some implementations, a dialysis system includes a dialysis machine with a fluid line and a drain line, a blood line set configured to be connected to the dialysis machine, and a drain apparatus coupled to the dialysis machine. The drain apparatus includes a chamber configured to receive an end of a patient line of the blood line set, an inlet line, an outlet line, and a valve. The inlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the fluid line of the dialysis machine. The outlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the drain line of the dialysis machine. The valve is configured to control flow of fluid through the outlet line.

The invention relates to an undulated thermostable hollow fiber membrane of reduced wall thickness, wherein the wall thickness amounts to 20 μm or greater and 30 μm or less and the waveform of the hollow fiber membrane exhibits a wavelength in the range of from more than 1 mm and less than 5 mm. In particular, the invention relates to a method for producing an undulated thermostable hollow fiber membrane of lower wall thickness.

The present disclosure relates to a water purification apparatus that comprises a reverse osmosis device, RO-device, producing a purified water flow and to a corresponding method. The proposed method comprises detecting at least one fluid property of purified water in the purified water path and regulating a flow rate of water in the recirculation path to fulfill one or more predetermined criteria of the purified water in the purified water path, based on the at least one detected fluid property. The present disclosure also relates to a computer program and a computer program product implementing the method.