Disclosed are various embodiments of a rocker-style treatment tank equipped with instrumentation. In one embodiment, a rocker treatment tank includes a dasher configured to oscillate within treatment liquid in the rocker treatment tank. The dasher includes a dasher shaft, one or more dasher arms coupled to the dasher shaft, and at least one dasher blade coupled to the dasher arm(s). The rocker treatment tank also includes one or more sensors configured to provide data directly or indirectly indicating a torque transmitted to the dasher to effect oscillation.

A method of coating particles includes dispensing particles into a vacuum chamber to form a particle bed in at least a lower portion of the chamber that forms a half-cylinder, evacuating the chamber through a vacuum port in an upper portion of the chamber, rotating a paddle assembly such that a plurality of paddles orbit a drive shaft to stir the particles in the particle bed, injecting a reactant or precursor gas through a plurality of channels into the lower portion of the chamber as the paddle assembly rotates to coat the particles, and injecting the reactant or precursor gas or a purge gas through the plurality of channels at a sufficiently high velocity such that the reactant or precursor a purge gas de-agglomerates particles in the particle bed.

A system for growing algae includes a pivot arm pivotally coupled to a pivot connection positioned in a pond containing water and algae, and a mixing device coupled to the pivot arm and extending into the pond to mix the water and the algae as the pivot arm rotates.

A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

The present disclosure belongs to the technical field of gel material processing, and discloses processing equipment and a processing technology of a gel microsphere material. The processing equipment comprises a mixing barrel, wherein a motor is installed at the top of the mixing barrel; a rotating rod is arranged in the mixing barrel; the rotating rod is fixedly connected to the output end of the motor; a fan-shaped impeller is installed at the bottom end of the rotating rod; the bottom of the rotating rod communicates with a gas conveying pipe; a shunting ring is fixedly connected to the inner side wall of the mixing barrel; the bottom of the rotating rod is fixedly connected with the fan-shaped impeller; and the gas conveying pipe is arranged at the bottom of the mixing barrel to inflate a raw material solution in the mixing barrel, when bubbles float in the solution, the solution can be stirred, and then under the cooperation of the fan-shaped impeller at the bottom of the rotating rod, the raw material solution of the gel microsphere material is stirred more quickly and more uniformly in the mixing barrel compared with the raw material solution only stirred by the fan-shaped impeller.

A microfluidic system and method suitable for liquid mixing. The microfluidic system uses a pump (400) as the driving source, which draws at least two liquid samples that are to be mixed into the pump (400). Some air is drawn into the pump (400) as well. The system is also comprised of a mixing reservoir (203). The two liquids drawn into the pump (400) are pushed into the mixing reservoir (203). The air bubbles generated by the air have a stirring effect on the mixed liquid in the mixing reservoir (203). After the air bubbles burst, left at rest, and the air has risen to the top of the mixing reservoir (203), the mixed liquid is drawn back to the pump (400) and fed to the outlet (103) for subsequent detection steps. The addition of an antifoaming agent will prevent the accumulation of air bubbles during the mixing process. In the system, the valves (501, 502, 503, 504) and the sensors (601, 602, 603, 604) in the microfluidic channels (301, 302, 303, 304) will be used for the operation of the microfluidic system and for the precise control of the flow.

A reactor for coating particles includes a stationary vacuum chamber having a lower portion that forms a half-cylinder and an upper portion to hold a bed of particles to be coated, a vacuum port in the upper portion of the chamber, a paddle assembly, a motor to rotate a drive shaft of the paddle assembly, a chemical delivery system to deliver a first fluid, and a first gas injection assembly to receive the first fluid from the chemical delivery system and having apertures configured to inject a first reactant or precursor gas into the lower portion of the chamber and such that the first reactant or precursor gas flows substantially tangent to a curved inner surface of the half-cylinder.

Methods and systems for chromatography are disclosed that employ a flexible container configured to fit within a support structure and adapted to receive a filtration or absorptive medium. The flexible container can include at least one inlet, at least one outlet, and a separation barrier peripherally sealed within the container to separate the container into a resin containing portion and a drainage portion. The barrier can be configured to exclude the resin material from the drainage portion while allowing fluids to pass therethrough. The disposable chromatography system can further include one or more agitators disposed within the flexible container and adjustably configured to be raised or lowered in the flexible container. When the agitator is in the raised position, the resin packing material can operate in a settled, packed-bed configuration. Alternatively, the agitator in the lowered position permits the chromatography resin packing material to operate in a mixed, slurry configuration.

The invention relates to a mixing chamber in which a first liquid comes into contact with a second liquid, and a gas injection device designed to inject a gas into the mixing chamber, wherein the gas injection device comprises: a gas source to provide the gas at a predetermined pressure, and a metering unit to limit the gas provided by the gas source to a predetermined flow rate, wherein the metering unit is in contact with the mixing chamber on a gas outlet side of the metering unit, wherein the gas outlet side of the metering unit comprises an elongated gap, wherein the gas passes out of the metering unit into the mixing chamber via the elongated gap, and wherein the gas passes out of the metering unit into the mixing chamber.

A system for oxygenating a biological culture includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween; a tubular member projecting into the compartment of the container and terminating at a terminal end; a gas supply coupled with the tubular member and being configured to blow gas through the tubular member; and a mixing element disposed within compartment of the container at a location between the terminal end of the tubular member and the bottom wall of the container, the mixing element being configured to mix the liquid.