Provided is a device for granulating, agglomerating, pelletising, drying and/or coating, the device including a swirl chamber, a distribution chamber, wherein the swirl chamber is separated from the distribution chamber by a base and wherein a powder to be granulated or a powder mixture to be granulated is presented in the swirl chamber, the device further including at least one agitator for thoroughly mixing the powder to be granulated or the powder mixture to be granulated and at least one addition device for a liquid, wherein the base is designed in several parts and at least one base part is horizontally and/or vertically displaceable, with the result that that the base becomes a distributor plate. Also provided is a method for granulating, agglomerating, pelletising, drying and/or coating using such a device and a base suitable for use as a distributor plate in a convective drying apparatus.

Provided is a device for granulating, agglomerating, pelletising, drying and/or coating, the device including a swirl chamber, a distribution chamber, wherein the swirl chamber is separated from the distribution chamber by a base and wherein a powder to be granulated or a powder mixture to be granulated is presented in the swirl chamber, the device further including at least one agitator for thoroughly mixing the powder to be granulated or the powder mixture to be granulated and at least one addition device for a liquid, wherein the base is designed in several parts and at least one base part is horizontally and/or vertically displaceable, with the result that that the base becomes a distributor plate. Also provided is a method for granulating, agglomerating, pelletising, drying and/or coating using such a device and a base suitable for use as a distributor plate in a convective drying apparatus.

A tool for dry mixing and coating of powder mixtures comprising includes a fixing shaft and an approximately disc-shaped element fixed thereto and of a diameter d, having an upper surface, a lower surface and a peripheral surface connecting the upper and lower surfaces. The disc-shaped element has a plurality of grooves extending parallel to the shaft axis. Each groove has two groove walls extending from the peripheral surface to a groove bottom. A tooth is formed between two grooves. In order to provide a tool which is suitable for particularly low contamination dry mixing, dry dispersing and coating of powder mixtures, the disc-shaped element has a base portion and at least one wear element fixed to the base portion, wherein at least one portion of each groove wall, that adjoins the peripheral surface, is formed by the wear element.

A tool for dry mixing and coating of powder mixtures comprising includes a fixing shaft and an approximately disc-shaped element fixed thereto and of a diameter d, having an upper surface, a lower surface and a peripheral surface connecting the upper and lower surfaces. The disc-shaped element has a plurality of grooves extending parallel to the shaft axis. Each groove has two groove walls extending from the peripheral surface to a groove bottom. A tooth is formed between two grooves. In order to provide a tool which is suitable for particularly low contamination dry mixing, dry dispersing and coating of powder mixtures, the disc-shaped element has a base portion and at least one wear element fixed to the base portion, wherein at least one portion of each groove wall, that adjoins the peripheral surface, is formed by the wear element.

A dry granulation process using a twin-screw extruder for granulating a powder mixture which includes at least one active ingredient and at least one carrier. The process includes steps of kneading the powder mixture in the screw barrel of the twin-screw extruder at a barrel temperature below a melting point of the at least one active ingredient and a melting point or a glass transition temperature of the at least one carrier to provide a kneaded powder mixture, and extruding the kneaded powder mixture to form granules. Granules and tablets produced using the dry granulation process in the twin-screw extruder are also provided.

A dry granulation process using a twin-screw extruder for granulating a powder mixture which includes at least one active ingredient and at least one carrier. The process includes steps of kneading the powder mixture in the screw barrel of the twin-screw extruder at a barrel temperature below a melting point of the at least one active ingredient and a melting point or a glass transition temperature of the at least one carrier to provide a kneaded powder mixture, and extruding the kneaded powder mixture to form granules. Granules and tablets produced using the dry granulation process in the twin-screw extruder are also provided.

The present disclosure generally relates to a reactor, in particular to a multiphase interface reactor applicable to chemistry, chemical industry, food, medicine, cosmetics and other fields. The reactor comprises a reaction cylinder; at least one feed port opened in the reaction cylinder; a stirring device, at least a part of the stirring device being located inside the reaction cylinder; at least one cylinder including a first cylinder and a second cylinder, wherein, the reaction cylinder, the first cylinder, and the second cylinder communicate with each other; an annular space is formed between the reaction cylinder and the second cylinder, so that at least part of a reaction product is allowed to enter the annular space from the reaction cylinder, and enter the first cylinder from the annular space; and at least one discharge port arranged on the first cylinder.

Provision of a manufacturing apparatus that can perform steps including a kneading step to a granulating step in one apparatus, can achieve a reduced size of the apparatus as a whole, and can reduce the variation in the diameter of kneaded granules. A manufacturing apparatus comprises: a kneading section feeding a kneaded material to a downstream side in the carrying direction while kneading a raw material; a granulating section performing granulation from the kneaded material generated in the kneading section.

Provision of a manufacturing apparatus that can perform steps including a kneading step to a granulating step in one apparatus, can achieve a reduced size of the apparatus as a whole, and can reduce the variation in the diameter of kneaded granules. A manufacturing apparatus comprises: a kneading section feeding a kneaded material to a downstream side in the carrying direction while kneading a raw material; a granulating section performing granulation from the kneaded material generated in the kneading section.

Disclosed are methods for forming boron nitride-containing aggregates that exhibit improved wear by attrition, and resulting filled polymers that exhibit significantly improved thermal conductivity. The boron nitride-containing aggregates are prepared according to a method that includes wet granulating boron nitride powder with a granulation solution to form wet boron nitride-containing granules; and drying the wet boron nitride-containing granules to cause evaporation of solvent in the granulation solution, thereby forming boron nitride-containing granules. Sintering achieves the desired boron nitride-containing aggregates.