An apparatus for producing prills includes a hollow body rotatable about a first axis, the body having a wall rotationally symmetrical around the first axis forming an interior space, the wall including nozzles for generating jets of liquid in a radially outward direction with respect to the first axis when rotating the hollow body; a second body disposed in the hollow body forming a gap between the hollow body and the second body; a liquid inlet for supplying a flow of liquid to the gap; a rotary drive unit for driving the hollow body around the first axis; a reciprocating drive-unit for reciprocally moving the hollow body and/or second body with respect to the other body along the first axis of rotation for applying reciprocal pressure on the jets; and a coupling for enabling relative rotations between the one of the hollow body and second body and the reciprocating drive-unit.

An apparatus for producing prills includes a hollow body rotatable about a first axis, the body having a wall rotationally symmetrical around the first axis forming an interior space, the wall including nozzles for generating jets of liquid in a radially outward direction with respect to the first axis when rotating the hollow body; a second body disposed in the hollow body forming a gap between the hollow body and the second body; a liquid inlet for supplying a flow of liquid to the gap; a rotary drive unit for driving the hollow body around the first axis; a reciprocating drive-unit for reciprocally moving the hollow body and/or second body with respect to the other body along the first axis of rotation for applying reciprocal pressure on the jets; and a coupling for enabling relative rotations between the one of the hollow body and second body and the reciprocating drive-unit.

Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.

Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.

A prilling bucket for prilling of a liquid, particularly for urea, comprising a rotating assembly, a vibrating assembly, a magnetostrictive actuator disposed to impart vibration to said vibrating assembly, wherein said magnetostrictive actuator is part of the rotating assembly and is firmly connected with said vibrating assembly and the bucket comprises a slip connector arranged to transfer electrical power to said actuator.

A prilling bucket for prilling of a liquid, particularly for urea, comprising a rotating assembly, a vibrating assembly, a magnetostrictive actuator disposed to impart vibration to said vibrating assembly, wherein said magnetostrictive actuator is part of the rotating assembly and is firmly connected with said vibrating assembly and the bucket comprises a slip connector arranged to transfer electrical power to said actuator.

Method of producing prills includes providing a hollow body rotatable about a first axis, the body having a wall rotationally symmetrical around the first axis forming an interior space, the wall including nozzles; providing a second body disposed in the hollow body such that a gap exists between the hollow body and the second body; supplying liquid to the gap; generating jets of liquid from the nozzles radially outward by driving the rotational motion of the hollow body and/or second body around the first axis of rotation using a rotary drive unit; applying a reciprocal pressure excitation on the jets of liquid by moving the hollow body and/or second body along the first axis; and decoupling the rotations of the one of the hollow body and second body and a reciprocating drive-unit.

The present invention provides, inter alia, for a liquid feeding device for the generation of droplets, in particular for the use in a process line for the production of freeze-dried particles, with a droplet ejection section for ejecting liquid droplets in an ejection direction, the droplet ejection section comprising at least one inlet port for receiving a liquid to be ejected, a liquid chamber for retaining the liquid, and a nozzle for ejecting the liquid from the liquid chamber to form droplets, wherein the liquid chamber is restricted by a membrane on one side thereof, the membrane being vibratable by an excitation unit, wherein the longitudinal axis of the liquid chamber is tilted relative to the longitudinal axis of the nozzle, and/or the liquid feeding device further comprises a deflection section for separating the droplets from each other by means of at least one gas jet, wherein the deflection section gas jet intersects perpendicular with an ejection path of the liquid ejected from the liquid chamber.

The present invention provides, inter alia, for a liquid feeding device for the generation of droplets, in particular for the use in a process line for the production of freeze-dried particles, with a droplet ejection section for ejecting liquid droplets in an ejection direction, the droplet ejection section comprising at least one inlet port for receiving a liquid to be ejected, a liquid chamber for retaining the liquid, and a nozzle for ejecting the liquid from the liquid chamber to form droplets, wherein the liquid chamber is restricted by a membrane on one side thereof, the membrane being vibratable by an excitation unit, wherein the longitudinal axis of the liquid chamber is tilted relative to the longitudinal axis of the nozzle, and/or the liquid feeding device further comprises a deflection section for separating the droplets from each other by means of at least one gas jet, wherein the deflection section gas jet intersects perpendicular with an ejection path of the liquid ejected from the liquid chamber.

The present invention comprises an apparatus and method for producing a microparticle and pharmaceutical compositions thereof. The apparatus and method rely on continuous inkjet (CIJ) printing to provide high quality microparticles at an improved rate.