An apparatus includes an integrated heat exchanger and reactor module. The integrated heat exchanger and reactor module includes a heat exchanger channel, and a reactor channel which is thermally coupled to the heat exchanger channel. The reactor channel includes a layer of catalyst material that is configured to produce hydrogen by endothermic catalytic decomposition of ammonia, which flows through the reactor channel, using thermal energy that is absorbed by the reactor channel from the heat exchanger channel.

Disclosed is a thermochemical reactor system and method for a temperature swing cyclic process with integrated heat recovery having at least two modules, wherein each module includes at least one chemical reaction zone and at least one thermal energy storage unit. The at least two modules are operationally connected for at least one heat transfer fluid for transporting heat between the two modules. Each chemical reaction zone includes at least one reacting material that undergoes in a reversible manner an endothermic reaction at temperature T.sub.endo and an exothermic reaction at temperature T.sub.exo, wherein T.sub.endo and T.sub.exo differ from each other. The at least one reacting material is provided in at least one encapsulation within each of the chemical reaction zones such that a contact of the reacting material and the at least one heat transfer fluid is avoided.

Heat exchanger-reformer for use in a hydrogen production plant for producing syngas, for instance by means of a steam methane reforming method, wherein the reformer comprises vessel with a first inlet for supplying feed and a second inlet for supplying hot reformer effluent, preferably coming from a main steam methane reformer, wherein the heat exchanger-reformer further comprises a heat exchanging section that is arranged in fluid connection with the first and second inlets for exchanging heat between the feed and reformer effluent to effectuate steam reforming of hydrocarbon to produce syngas, wherein the heat exchanging section comprises a plate heat exchanger assembly for heat exchange between said feed and said reformer effluent.

A thermochemical labyrinth reactor is disclosed. The reactor has a reoxidation zone and a reduction zone with electric heaters. A recuperation zone connects the reduction and reoxidation zones with first and second channels, the first channel adjoining the second channel, being separated by windows allowing an exchange of thermal radiation between channels while preventing gas exchange. The reactor also includes reactor plates composed of a reactive material, and a transit system running through the three zones, with the transit system configured to shuttle the plates between the reduction zone and the reoxidation zone, moving the plates along a circuit. The reactor also has a feedstock gas emitter to introduce a feedstock gas flowing opposite the movement of the plates. A gas extractor is configured to extract a product gas resulting from the feedstock gas being split by the oxidizing reactive material. All three zones are surrounded by an insulating housing.

An apparatus includes an integrated heat exchanger and reactor module. The integrated heat exchanger and reactor module includes a heat exchanger channel, and a reactor channel which is thermally coupled to the heat exchanger channel. The reactor channel includes a layer of catalyst material that is configured to produce hydrogen by endothermic catalytic decomposition of ammonia, which flows through the reactor channel, using thermal energy that is absorbed by the reactor channel from the heat exchanger channel.

The present invention provides a continuous upstream manufacturing process for the production of bispecific antibody products, which comprise at least two binding domains. The process comprises at least the steps of (i) providing in a perfusion bioreactor at least one mammalian cell culture, which is capable of expressing the bispecific antibody product, (ii) growing the mammalian cell culture at a first perfusion rate until a set point viable cell density is reached, and (iii) maintaining perfusion culture at a second perfusion rate, wherein the bispecific antibody product concentration in the bioreactor is kept below a threshold value. The bispecific antibody product is then subject to subsequent downstream processing. Moreover, the invention provides a bispecific antibody product produced by the continuous upstream manufacturing process.

Heat exchanger-reformer for use in a hydrogen production plant for producing syngas, for instance by means of a steam methane reforming method, wherein the reformer comprises vessel with a first inlet for supplying feed and a second inlet for supplying hot reformer effluent, preferably coming from a main steam methane reformer, wherein the heat exchanger-reformer further comprises a heat exchanging section that is arranged in fluid connection with the first and second inlets for exchanging heat between the feed and reformer effluent to effectuate steam reforming of hydrocarbon to produce syngas, wherein the heat exchanging section comprises a plate heat exchanger assembly for heat exchange between said feed and said reformer effluent.

The present invention relates to a thermochemical reactor system for a temperature swing cyclic process with integrated heat recovery comprising at least two modules, wherein each module comprises at least one chemical reaction zone (CRZ) and at least one thermal energy storage unit (TES), wherein the at least two modules are operationally connected for at least one heat transfer fluid (HTF) for transporting heat between the two modules, wherein each chemical reaction zone (CRZ) comprises at least one reacting material that undergoes in a reversible manner an endothermic reaction at temperature T.sub.endo and an exothermic reaction at temperature T.sub.exo, wherein T.sub.endo and T.sub.exo differ from each other, wherein the at least one reacting material is provided in at least one encapsulation within each of the chemical reaction zones (CRZ) such that a contact of the reacting material and the at least one heat transfer fluid is avoided. The present invention relates further to a method for operating such a reactor system.

A thermochemical labyrinth reactor is disclosed. The reactor has a reoxidation zone and a reduction zone with electric heaters. A recuperation zone connects the reduction and reoxidation zones with first and second channels, the first channel adjoining the second channel, being separated by windows allowing an exchange of thermal radiation between channels while preventing gas exchange. The reactor also includes reactor plates composed of a reactive material, and a transit system running through the three zones, with the transit system configured to shuttle the plates between the reduction zone and the reoxidation zone, moving the plates along a circuit. The reactor also has a feedstock gas emitter to introduce a feedstock gas flowing opposite the movement of the plates. A gas extractor is configured to extract a product gas resulting from the feedstock gas being split by the oxidizing reactive material. All three zones are surrounded by an insulating housing.

Reactor-exchanger comprising at least 3 stages with, on each stage, at least one area promoting the heat exchanges and at least one distribution area upstream and/or downstream of the area promoting the heat exchanges, characterized in that the area promoting the heat exchanges comprises cylindrical millimetric channels, there being 1 to 1000 of said channels with a length of between 10 mm and 500 mm.