Coating material combination consisting of a coating material for forming a surfacer coat and a coating material for forming a topcoat, and use thereof for producing a coating system consisting of a surfacer coat and topcoat on a substrate. The substrate preferably comprises the body or the cabin of a motor vehicle, or a constituent thereof. The coating material combination of the invention is suitable especially for producing coatings consisting of a cured surfacer coat and a cured topcoat on automobiles and commercial vehicles, such as trucks, vans, or buses.

Provided herein are poly(ether ester) multi-block copolymers (PEE-MBCP). Also provided herein are injectable delivery systems or pharmaceutical compositions, comprising a PEE-MBCP provided herein, either alone or in combination with a binding protein, such as abicipar. Also provided herein are methods of using these injectable delivery systems or pharmaceutical compositions provided herein for the treatment of ocular disorders.

Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-).sub.p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.

A vehicle wiper blade comprises a blade support part and a lip part coupled swingably with the blade support part via a neck. The lip part comprises polyurethane. The polyurethane comprises a reactant of a composition including an isocyanate compound which includes diisocyanate and tri- or higher functional polyfunctional isocyanate, and an alcohol which includes tri- or higher functional polyfunctional alcohol. The diisocyanate has an aromatic ring in a molecule. When a molecule of the polyurethane is ionized with a mass spectrometer of a direct sample injection system, then obtained M1, M2 and M3 satisfy the following relation: M2/M1 is 0.001 to 0.028, M3/M1 is 0.020 to 0.110, and M2/M3 is 0.013 to 0.300, and a concentration of the polyfunctional alcohol in the polyurethane is 0.12 mmol/g to 0.65 mmol/g.

The present disclosure provides a jet-black multilayer coating film having excellent properties in high appearance, water resistance, and humidity resistance and comprising a base coating film and a clear coating film formed by a coating composition containing a plant-derived aliphatic polyester mainly and a method for forming the same. A jet-black multilayer coating film comprising a base coating film layer formed by a base coating composition which contains a polyester polyol (A-1) containing a polyol having three or more functions and lactic acid as a consisting component of 80 mol % or more and having a hydroxyl value of 140 to 240 mgKOH/g wherein 70 mol % or more of the hydroxyl groups are secondary hydroxyl groups, an acrylic resin (A-2) with a hydroxyl value of 30 to 80 mgKOH/g and a glass transition point of 40 to 80° C., and a polyisocyanate (A-3), and a clear coating film layer formed on said base coating film layer by a clear coating composition which contains a polyester polyol (B-1) obtained by polymerization of a raw composition of a polyol having three or more functions, sebacic acid, and a diol and having a hydroxyl value of 140 to 240 mgKOH/g, an acrylic resin (B-2) with a hydroxyl value of 120 to 220 mgKOH/g, and a polyisocyanate (B-3).

The present disclosure relates to methods for making polyols, esters, and surfactants. Generally, a carboxyl-containing molecule is reacted with an epoxide-containing molecule to obtain a hydroxylated ester. If multiple epoxide groups are present in the epoxide-containing molecule, the resulting molecule can also be considered a polyol. The hydroxyl groups can be further ethoxylated to obtain a surfactant/stabilizer.

A crosslinkable composition is useful for preparing a skin contact adhesive or a coating on a substrate. The crosslinkable composition includes (A) a polyurethane-polyorganosiloxane copolymer and (B) a curing catalyst. The skin contact adhesive prepared by crosslinking the crosslinkable composition is useful in applications such as adhesives for medical tapes, adhesives for wound dressings, adhesives for prosthetics, ostomy appliance adhesives, adhesives for medical monitoring appliances, adhesives for scar therapy treatments, adhesives for cosmetic patches, and transdermal drug delivery systems.

Bioactive liquid formulations are formed of combinations of absorbable, segmented aliphatic polyurethane compositions and liquid polyether for use as vehicles for the controlled release of at least one active agent for the conventional and unconventional treatment of different forms of cancer and the management of at least one type of bacterial, fungal, and viral infection.

Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-).sub.p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.

Provided are oriented biodegradable thermoplastic polyurethane films. The films may be prepared by extruding and drawing biodegradable polyurethane films. The polyurethanes may be prepared from biodegradable polyols and/or biodegradable chain extenders. The films possess high tensile strength yet are degradable under biological conditions. The films may be utilized in the fabrication of devices, particularly implantable medical devices.