The present invention relates to accurately determining a contour of a depolarizing region.

An image processing apparatus extracts a depolarizing region in a polarization-sensitive tomographic image of a subject's eye, and detects, in a tomographic intensity image of the subject's eye, a region corresponding to the extracted depolarizing region. The tomographic intensity image corresponds to the polarization-sensitive tomographic image,

A method of assessing tissue health comprises the steps of obtaining depth-resolved spectra of a selected area of in vivo tissue, and assessing the health of the selected area based on the depth-resolved structural information of the scatterers. Obtaining depth-resolved spectra of the selected area comprises directing a sample beam towards the selected area at an angle, and receiving an angle-resolved scattered sample beam. The angle-resolved scattered sample beam is cross-correlated with the reference beam to produce an angle-resolved cross-correlated signal about the selected area, which is spectrally dispersed to yield an angle-resolved, spectrally-resolved cross-correlation profile having depth-resolved information about the selected area. The angle-resolved, spectrally-resolved cross-correlation profile is processed to obtain depth-resolved information about scatterers in the selected area.

Multichannel optical coherence systems and methods involving optical coherence tomography (OCT) subsystems are operably and respectively connected to optical fibers of a multichannel optical probe, such that each optical fiber forms at least a distal portion of a sample beam path of a respective OCT subsystem. The optical fibers are in optical communication with distal optical elements such that external beam paths associated therewith are directed towards a common spatial region external to the housing. Image processing computer hardware is employed to process OCT signals obtained from the plurality of OCT subsystems to generate an OCT image dataset comprising a plurality of OCT A-scans and process the OCT image dataset to generate volumetric image data based on known positions and orientations of the external beam paths associated with the OCT subsystems.

Systems, methods, and devices for directed to duplex imaging techniques for combining high-resolution surface images obtained with a Scanning Fiber Endoscope (SFE), and high-resolution penetrating OCT images obtained through Optical Coherence Tomography (OCT), from a SFE, and interleaving frames to improve resolution and identify below surface information of biological structures.

In an aspect, a method for imaging a target comprises steps of: performing optical coherence tomography (OCT) scanning on the target with one or more beams of source light, the one or more beams of source light comprising a plurality of wavelengths; wherein performing OCT scanning comprises: providing the source light to a reference optical path and to a sample optical path, wherein providing the source light to a sample optical path comprises illuminating the target with the source light; and recording interference data corresponding to an interaction of a light from the reference optical path and a light from the sample optical path; processing the interference data; and identifying blood or one or more blood-features in the target based on an optical attenuation of light in or associated with the sample optical path by the blood or the one or more blood-features.

An analysis apparatus includes an acquisition part that acquires a plurality of interference images based on lights having a plurality of different wavelengths from an interference measurement apparatus, a removing part that outputs an interference component by removing a non-interference component included in an interference signal for each pixel in the plurality of the interference images, a conversion part that generates an analysis signal by performing a Hilbert transformation on the interference component, and a calculation part that calculates a distance between a reference surface and a surface of an object to be measured by specifying a phase gradient of a wavelength of light radiated onto the reference surface and the surface of the object to be measured on the basis of the interference component and the analysis signal.

An information processing apparatus that executes processing of obtaining, from an interference fringe image that is a two-dimensional distribution of intensity of interference fringes of object light and reference light, a phase difference image that is a two-dimensional distribution of a phase difference between the object light and the reference light, and obtaining a shape of an object to be observed based on the phase difference image includes at least one processor configured to acquire object-related information regarding the object to be observed, read out, from a storage unit in which the object-related information and a shape profile indicating the shape of the object to be observed are stored in association with each other, the shape profile corresponding to the acquired object-related information, and perform phase connection with respect to the phase difference image with reference to the read-out shape profile.

The technology disclosed in this patent document can be used to implement an optical coherent tomography (OCT) system that combines a control of the probe light to the target sample with different optical aberration patterns in optically probing the target sample and an OCT imaging processing to enhance the OCT imaging quality by combining image signals from in-phase contributions from the probing with different optical aberration patterns while suppressing randomly phased contributions from scattering by the target sample.

An OCT examination device for recording an object comprises an OCT radiation source which emits OCT radiation, an OCT beam path, a housing, an exit opening formed in the housing for the OCT radiation of the OCT radiation source, an OCT exit direction of the radiation through the exit opening, a control unit connected to the OCT radiation source OCT radiation and configured to record a multiplicity of measurement profiles mutually separated in a recording period and, within the recording period, to drive the OCT radiation source in order to emit the OCT radiation and the OCT radiation receiver in order to receive the backscattered OCT radiation, and to keep an OCT output direction and an OCT exit direction constant with respect to one another in their angular orientation during the recording period.

A laser transmission apparatus utilizing multiple laser beams and beam paths with a diverger lens to provide an illumination pattern that can compensate for lateral movement of the platform during shearography is provided. Further, this optical setup requires no moving parts and does not reduce power of the laser beams as they move through the individual components thereof. From the perspective of the surface being scanned or inspected, the present disclosure may provide two laser images of a single surface that appear to be identical despite the fact that they were taken from two different spatial positions of the moving platform.