A method of measuring rinse properties of a composition from a surface, the method includes providing a cosmetic treatment composition. The method also includes applying the cosmetic treatment composition to a surface. The method also includes rinsing the surface with a first amount of water after applying the cosmetic treatment composition to the surface. The method also includes collecting a portion of the first amount of water after rinsing the surface with the first amount of water. The method also includes measuring a first turbidity of the portion of the first amount of water after collecting the portion of the first amount of water.

A method is provided herein that discloses receiving, by a processor, first image data comprising first bioluminescence data derived from an organism at a first time, receiving, by the processor, second image data comprising second bioluminescence data derived from an organism at a second time, comparing, by the processor, the first image data to the second image data, determining, by the processor, whether a peak light output event has occurred based on the comparison, and outputting, by the processor and to a display device, an indication that the peak light output event has occurred.

A system includes a light source, a first lens, a second lens, a third lens, a beam splitter, a first image collection device, and a second image collection device. The first lens is configured to collimate a light beam and to direct the collimated light beam through a test sample. The beam splitter is configured to split the light beam from the test sample and to transmit a first portion of the light beam toward the second lens and reflect a second portion of the light beam toward the third lens. The first image collection device is positioned adjacent to a first obstruction and configured to record an obstructed first image formed by the first portion of the light beam. The second image collection device is positioned adjacent to a second obstruction and configured to record an obstructed second image formed by the second portion of the light beam.

The present invention relates to an optical nanostructure sensing device and an image analysis method. The image analysis method includes: illuminating a light beam from a predetermined incident angle onto a nanostructure pixel sensor; capturing images of the nanostructure pixel sensor when applying an analyte on the nanostructure pixel sensor; obtaining a relationship of periodic spacing and brightness from each of the images; and obtaining wavelength values from the relationship of periodic spacing and brightness at a predetermined brightness value; and determining a sensing process based on a wavelength shift of the wavelength values. The nanostructure pixel sensor includes a plurality of the nanostructure pixels, each of the nanostructure pixels includes periodic nanostructures, and the relationship of periodic spacing and brightness is based on the brightness of the nanostructure pixels having different periodic spacings.

Exemplified methods and systems facilitate presentation of data derived from measurements of endotoxins in fluid samples. In particular, the exemplified methods and systems facilitate presentation of such measurements in a graphical user interface and/or in a report for endotoxin concentrations in a fluid sample. The presentation facilitates a unified and intuitive graphic visualization that are presented within a single interactive interface and/or report.

An object of the present invention is to suppress time and effort into generating a calibration curve while ensuring accuracy of the calibration curve in an analysis step of generating the calibration curve by using two or more standard solutions (two or more concentrations). A calibration curve generation method according to the present invention includes acquiring time course data by irradiating a mixed reaction liquid obtained by mixing one standard solution containing a component to be measured having a concentration other than a zero concentration and a reagent reacting with the component to be measured with light and measuring a turbidity change over time of the mixed reaction liquid, extracting pieces of light amount data in a plurality of different times from a fitting line obtained by complementing discrete portions of the time course data, and generating the calibration curve indicating a relationship between the plurality of pieces of light amount data and a plurality of concentrations by converting the plurality of different times into the plurality of concentrations of the component to be measured (FIG. 1).

Surface plasmon resonance-based methods for detecting and characterizing preexisting and/or treatment-induced anti-viral vector antibodies against viral vector-based gene therapy compositions in a biological sample from a subject are described.

Provided herein are methods of determining binding kinetics of a ligand. In some embodiments, the methods include contacting the ligand with a first surface of a substrate, which first surface comprises an electrically conductive coating and a population of virions connected to the first surface via one or more linker moieties, wherein viral envelopes of the virions display one or more proteins that bind, or are capable of binding, to the ligand, applying an alternating current electric field to the substrate to induce the virions to oscillate proximal to the first surface of the substrate, and detecting changes in oscillation amplitudes of the virions over a duration. Related virion oscillator array devices, systems and computer readable media are also provided.

The present invention relates to an optical nanostructure sensing device and an image analysis method. The image analysis method includes: illuminating a light beam from a predetermined incident angle onto a nanostructure pixel sensor; capturing images of the nanostructure pixel sensor when applying an analyte on the nanostructure pixel sensor; obtaining a relationship of periodic spacing and brightness from each of the images; and obtaining wavelength values from the relationship of periodic spacing and brightness at a predetermined brightness value; and determining a sensing process based on a wavelength shift of the wavelength values. The nanostructure pixel sensor includes a plurality of the nanostructure pixels, each of the nanostructure pixels includes periodic nanostructures, and the relationship of periodic spacing and brightness is based on the brightness of the nanostructure pixels having different periodic spacings.

Provided herein are methods of determining molecular binding kinetics on particles, such as magnetic nanoparticles. In some embodiments, the methods include introducing an incident light from a light source toward a sample container that comprises a particle-bound biomolecule-ligand composition comprising a plurality of particle-bound biomolecules and a plurality of ligands that binds, or is capable of binding, to biomolecules of the plurality of particle-bound biomolecules, detecting light scattered from particle-bound biomolecule-ligand complexes in the particle-bound biomolecule-ligand composition over a duration to produce a set of imaging data using the detector, and determining size or volume changes of one or more of the particle-bound biomolecule-ligand complexes during at least a portion of the duration from the set of imaging data to thereby determine the molecular binding kinetics on the particles. Related systems and computer readable media are also provided.