Method and apparatus for neuroenhancement to facilitate learning and performance
11717686 · 2023-08-08
Assignee
Inventors
Cpc classification
A61B5/0053
HUMAN NECESSITIES
A61B5/7264
HUMAN NECESSITIES
G16H50/20
PHYSICS
A61B5/4094
HUMAN NECESSITIES
A61B5/0816
HUMAN NECESSITIES
A61N1/0456
HUMAN NECESSITIES
A61N1/36082
HUMAN NECESSITIES
A61M2230/005
HUMAN NECESSITIES
A61B5/374
HUMAN NECESSITIES
A61M21/02
HUMAN NECESSITIES
A61B5/7425
HUMAN NECESSITIES
A61B5/743
HUMAN NECESSITIES
A61N1/37205
HUMAN NECESSITIES
A61B5/055
HUMAN NECESSITIES
G01T1/2985
PHYSICS
A61M2230/005
HUMAN NECESSITIES
A61B5/4836
HUMAN NECESSITIES
G16H50/70
PHYSICS
A61B5/24
HUMAN NECESSITIES
A61B5/16
HUMAN NECESSITIES
International classification
A61B5/00
HUMAN NECESSITIES
A61B5/24
HUMAN NECESSITIES
A61N1/05
HUMAN NECESSITIES
A61N1/372
HUMAN NECESSITIES
Abstract
A method of facilitating a skill learning process or improving performance of a task, comprising: determining a brainwave pattern reflecting neuronal activity of a skilled subject while engaged in a respective skill or task; processing the determined brainwave pattern with at least one automated processor; and subjecting a subject training in the respective skill or task to brain entrainment by a stimulus selected from the group consisting of one or more of a sensory excitation, a peripheral excitation, a transcranial excitation, and a deep brain stimulation, dependent on the processed temporal pattern extracted from brainwaves reflecting neuronal activity of the skilled subject.
Claims
1. A method of facilitating a process of learning a skill, comprising: determining brain wave electrical activity patterns of a first subject skilled in the skill, the brain wave electrical activity patterns being selectively associated with a cognitive state representing a readiness for training in a physical activity involving the skill; processing the brain wave electrical activity patterns of the first subject with at least one microprocessor, to determine the cognitive state representing the readiness for training in the skill; subjecting a second subject, while learning to perform the physical activity involving the skill, to a neurostimulation having at least one stimulus selectively dependent on the processed brain wave electrical activity patterns of the first subject, the neurostimulation being adapted to induce in the second subject a spatial brain activity pattern over time corresponding to the cognitive state representing the readiness for training in the skill; determining spatial brain wave electrical activity patterns of the second subject over time while subject to the neurostimulation; and adaptively controlling said neurostimulation to which the second subject is subjected, dependent on the determined spatial brain wave electrical activity patterns of the second subject over time, to alter a timing of said neurostimulation to synchronize an electrical phase of the processed brain wave electrical activity patterns of the first subject with the determined brain wave electrical activity patterns of the second subject while engaged in an activity involving the skill.
2. The method according to claim 1, wherein said at least one stimulus is selected from the group consisting of one or more of a sensory excitation, a peripheral excitation, a cranial electrotherapy stimulation (CES), a transcranial electric stimulation (TES), transcranial magnetic stimulation (TMS), and a deep brain stimulation (DBS).
3. The method according to claim 1, further comprising determining a neuronal baseline activity of the first subject, while not engaged in the skill.
4. The method according to claim 1, wherein the neurostimulation is a visual excitation.
5. The method according to claim 1, wherein the processing comprises performing a hybrid time-frequency domain transform on the brain wave electrical activity patterns of the first subject.
6. The method according to claim 1, wherein the neurostimulation is further dependent on a concurrent state of the second subject.
7. The method according to claim 1, further comprising determining brain wave electrical activity patterns of the second subject, wherein the neurostimulation is synchronized with the determined brain wave electrical activity patterns of the second subject.
8. The method according to claim 1, wherein said brain wave electrical activity patterns are obtained by at least one of electroencephalography (EEG), low-resolution brain electromagnetic tomography, and magnetoencephalography.
9. The method according to claim 1, wherein the neurostimulation is an auditory excitation.
10. The method according to claim 1, wherein the brain wave electrical activity patterns are determined over time and space, and the processing comprises performing a transform from a time and space domain on a representation of the brain wave electrical activity patterns.
11. The method according to claim 1, wherein the neurostimulation is adapted to cause a brainwave entrainment of the second subject with the first subject.
12. The method according to claim 1, wherein the skill comprises at least one of a mental, motor, musical instrument playing, singing, dancing, sports, martial arts, speech, mathematical, calligraphical, drawing, painting, massage, assembly, walking, running, swimming, yoga, fighting, shooting, self-defense, olfactory, and muscular coordination skill.
13. An apparatus for facilitating a skill learning process, comprising at least one automated processor, configured to: process information derived from brain wave patterns representing electrical activity of the brain of a first subject while engaged in a skill to determine a cognitive state corresponding to a readiness of the first subject for training in the skill, and in dependence thereon, define a neural stimulus pattern, the neural stimulus pattern representing a modulation of a waveform of at least one stimulus of a stimulation device for stimulation of a second subject during performance of the skill, adapted to induce the cognitive state corresponding to readiness for training in the skill in the second subject and effective to improve at least one of learning and performance of the skill by the second subject receiving stimulation with the neural stimulus pattern; at least one of store and output the defined neural stimulus pattern; determine spatial brain wave electrical activity patterns of the second subject over time while subject to the neural stimulus pattern; and control said at least one stimulus selectively dependent on the determined spatial brain wave electrical activity patterns of the second subject over time to adaptively modify the at least one stimulus to synchronize an electrical phase of a representation of the brain wave electrical activity patterns of the first subject while engaged in an activity involving the skill in the at least one stimulus, with the determined spatial brain wave electrical activity patterns of the second subject over time.
14. The apparatus according to claim 13, further comprising the stimulation device, configured to subject the second subject to the neural stimulus pattern adapted to induce the cognitive state corresponding to the readiness for training in the skill in the second subject.
15. The apparatus according to claim 13, wherein the neural stimulus pattern comprises at least one stimulus selected from the group consisting of one or more of a sensory excitation, a peripheral excitation, a transcranial excitation, and a deep brain stimulation.
16. The apparatus according to claim 13, wherein the neural stimulus pattern is responsive to at least a brain wave pattern representing electrical activity of the brain of the second subject prior to application of the stimulation of the second subject.
17. The apparatus according to claim 13, wherein the neural stimulus pattern is adaptive to at least a brain wave pattern representing electrical activity of the brain of the second subject subsequent to initiation of the stimulation of the second subject.
18. The apparatus system according to claim 13, wherein the brain wave patterns representing electrical activity of the brain of the first subject are obtained by a device comprising at least 19 electrodes.
19. The apparatus according to claim 13, wherein the at least one processor is further configured to: determine brain wave patterns selectively associated with the skill and the cognitive state corresponding to the readiness for training in the skill, by analysis of spatial brain wave electrical activity patterns over time of the first subject while preparing for and while being engaged in the skill, and determine brain wave patterns of the second subject corresponding to the determined brain wave patterns selectively associated with the skill and the cognitive state corresponding to the readiness for training in the skill of the first subject.
20. The apparatus according to claim 13, wherein the at least one processor comprises at least one single-instruction multiple-data (SIMD) type processor, and is further configured to determine brain wave patterns which represent the cognitive state corresponding to the readiness for training in the skill by analysis of a spatial brain activity pattern over time of the first subject prior to engaging in the skill, the analysis comprising at least one of a statistical analysis and machine learning of the spatial brain activity pattern over time with the at least one single-instruction multiple-data (SIMD) type processor.
21. The apparatus according to claim 20, wherein the at least one processor is further configured to define the neural stimulus pattern by analysis of a spatial brain wave activity pattern over time of the second subject, and translate the determined spatial brain activity pattern over time of the first subject which represent the cognitive state representing the readiness for training in the skill according to at least one transform of the spatial brain wave activity pattern over time of the second subject from a space-time domain, to define the neural stimulus pattern for the second subject to achieve a spatial brain activity pattern over time in the second subject corresponding to the cognitive state representing the readiness for training in the skill.
22. The apparatus according to claim 13, further comprising a memory configured to store a brain wave pattern model, wherein the at least one processor is configured to further define the neural stimulus pattern in dependence on the stored brain activity model.
23. A non-transitory computer-readable medium, storing therein instructions for a programmable processor to automatically perform a process, comprising: instructions for synchronizing brain wave electrical activity data of a first subject with at least one physical activity event involving the first subject; instructions for analyzing the brain wave electrical activity data of the first subject to determine brain activity data over time corresponding to cognitive state representing a readiness for training in the physical activity event; instructions for analyzing the brain activity data to determine a selective change in the brain activity data over time corresponding to the performance of the physical activity event; instructions for determining a stimulation pattern adapted to induce a brain wave electrical activity in a second subject having a correspondence to the brain wave electrical activity data associated with the cognitive state representing the readiness for training in the physical activity event, followed by performance of the physical activity event; instructions for monitoring a spatial brain wave electrical activity in the second subject over time after commencement of the application of the stimulation pattern; and instructions for adaptively controlling the stimulation pattern dependent on the monitored brain wave electrical activity in the second subject over time, to synchronize an electrical phase timing of a representation of the brain wave electrical activity data of the first subject during performance of the physical activity event in the stimulation pattern with the determined brain wave electrical activity of the second subject.
24. The non-transitory computer-readable medium according to claim 23, further comprising instructions for determining the stimulation pattern further based on at least a brain wave electrical activity model.
25. The non-transitory computer-readable medium according to claim 23, further comprising: instructions for storing data describing a spatial and temporal pattern extracted from the brain wave electrical activity of the first subject, the stored spatial and temporal pattern being adapted for modulation of at least one signal usable as the stimulation pattern for the second subject, to facilitate learning relating to performance of the physical activity event by the second subject after achieving the cognitive state representing the readiness of the second subject for training relating to performance of the physical activity event is achieved in the second subject.
26. The non-transitory computer-readable medium according to claim 23, wherein the physical activity event involves performance of an artistic skill.
27. The non-transitory computer-readable medium according to claim 23, wherein the physical activity event involves performance of a motor skill.
28. The non-transitory computer-readable medium according to claim 23, further comprising: instructions for stimulating the second subject with the determined stimulation pattern to induce the brain activity in the second subject having the correspondence to the brain activity data associated with achieving the cognitive state representing the readiness for training related to performance of the physical activity event, followed by performance of the physical activity event.
29. A method of facilitating a process of learning a physical motor skill, comprising: determining a brain wave electrical activity pattern of a first subject skilled in the physical motor skill comprising a cognitive state representing a readiness for training in the physical motor skill, and while engaged in an activity involving the physical motor skill; processing the brain wave electrical activity pattern of the first subject; subjecting the second subject learning the physical motor skill to a neurostimulation after said processing, comprising a sequence of stimuli selectively dependent on the processed brain wave electrical activity pattern of the first subject, to initially induce in the second subject the brain wave electrical activity pattern corresponding to the cognitive state representing the readiness for training in the physical motor skill, and subsequently the brain wave electrical activity pattern corresponding to a cognitive state representing performance of the activity involving the physical motor skill; controlling said neurostimulation of the second subject, selectively dependent on a concurrent spatial brain wave electrical activity of the second subject over time, to adaptively synchronize an electrical phase of a representation of the brain wave electrical activity patterns of the first subject while engaged in performance of the activity involving the physical motor skill represented in the neurostimulation, with the concurrent brain wave electrical activity patterns of the second subject.
30. An apparatus for facilitating a skill learning process, comprising: means for processing information derived from an electromagnetic brain wave pattern of a first subject while preparing to perform a task involving the skill, comprising a brain wave pattern corresponding to a cognitive state of readiness for training in the task, and subsequently a cognitive state while engaged in performance of the task, and selectively in dependence thereon, define a neural stimulus pattern sequence representing a modulation of a waveform of at least one stimulus for stimulation of a second subject, effective to generate the cognitive state of readiness for training in the task, to improve readiness for training in performance of the task, and subsequently at least one of learning and performance of the task by the second subject receiving stimulation with the neural stimulus pattern; means for controlling the neural stimulus pattern sequence delivered to the second subject, to adaptively synchronize an electrical phase of a representation of the brain wave patterns of the first subject while engaged in the at least one of learning and performance of the task, selectively dependent on concurrent spatial brain wave patterns of the second subject, with the concurrent brain wave patterns of the second subject over time; means for monitoring a spatial brain wave pattern over time of the second subject after commencement of the application of the neural stimulus pattern, and to adapt the neural stimulus pattern based on feedback dependent on the monitored spatial brain wave pattern over time of the second subject; and at least one of: at output port configured to present the defined neural stimulus pattern; a memory configured to store the defined neural stimulus pattern; and a stimulator configured to stimulate the second subject according to the defined neural stimulus pattern.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) The detailed description is described with reference to the accompanying figures. In the figures, the left-most digit(s) of a reference number identifies the figure in which the reference number first appears. The use of the same reference number in different figures indicates similar or identical items.
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
(19)
(20)
(21)
(22)
(23)
(24)
(25)
(26)
(27)
(28)
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
(29) The present invention generally relates to enhancing emotional response by a subject in connection with the received information by conveying to the brain of the subject temporal patterns of brainwaves of a second subject who had experienced such emotional response, said temporal pattern being provided non-invasively via light, sound, transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tDAS) or HD-tACS, transcranial magnetic stimulation (TMS) or other means capable of conveying frequency patterns.
(30) The transmission of the brain waves can be accomplished through direct electrical contact with the electrodes implanted in the brain or remotely employing light, sound, electromagnetic waves and other non-invasive techniques. Light, sound, or electromagnetic fields may be used to remotely convey the temporal pattern of prerecorded brainwaves to a subject by modulating the encoded temporal frequency on the light, sound or electromagnetic filed signal to which the subject is exposed.
(31) Every activity, mental or motor, every emotion is associated with unique brainwaves having specific spatial and temporal patterns, i.e., a characteristic frequency or a characteristic distribution of frequencies over time and space. Such waves can be read and recorded by several known techniques, including electroencephalography (EEG), magnetoencephalography (MEG), exact low-resolution brain electromagnetic tomography (eLORETA), sensory evoked potentials (SEP), fMRI, functional near-infrared spectroscopy (fNIRS), etc. The cerebral cortex is composed of neurons that are interconnected in networks. Cortical neurons constantly send and receive nerve impulses-electrical activity-even during sleep. The electrical or magnetic activity measured by an EEG or MEG (or another device) device reflects the intrinsic activity of neurons in the cerebral cortex and the information sent to it by subcortical structures and the sense receptors.
(32) An EEG electrode will mainly detect the neuronal activity in the brain region just beneath it. However, the electrodes receive the activity from thousands of neurons. One square millimeter of cortex surface, for example, has more than 100,000 neurons. It is only when the input to a region is synchronized with electrical activity occurring at the same time that simple periodic waveforms in the EEG become distinguishable. The temporal pattern associated with specific brainwaves can be digitized and encoded a non-transient memory.
(33) “Playing back the brainwaves” to another animal or person by providing decoded temporal pattern through tDCS, tACS, HD-tACS, TMS, or through electrodes implanted in the brain, allows the recipient to learn the task at hand faster. For example, if the brain waves of a mouse navigated a familiar maze are decoded (by EEG or via implanted electrodes), playing this temporal pattern to another mouse unfamiliar with this maze will allow it to learn to navigate this maze faster.
(34) Employing light, sound or electromagnetic field to remotely convey the temporal pattern of brainwaves (which may be prerecorded) to a subject by modulating the encoded temporal frequency on the light, sound or electromagnetic filed signal to which the subject is exposed.
(35) When a group of neurons fires simultaneously, the activity appears as a brainwave. Different brainwave-frequencies are linked to different tasks in the brain.
(36)
(37)
(38)
(39)
(40)
(41)
(42)
(43)
(44)
(45)
(46)
(47)
(48)
(49)
(50)
(51)
(52)
(53)
(54)
(55)
(56)
(57)
(58)
(59)
Example 1
(60) We record EEG of a concert pianist while the pianist is playing a particular piece (e.g., Beethoven sonata); then decode the dynamic spatial and/or temporal patterns of the EEG and encode them in software. If a music student wants to learn this particular Beethoven sonata, we use the software with an encoded dynamic temporal pattern to drive “smart bulbs” or another source of light while the student is learning to play this piece from the music sheet. The result is accelerated learning. See
Example 2
(61) We record EEG of a martial art master while performing a particular move (say Karate or Kong Fu), decode the dynamic spatial and temporal patterns of the EEG and encode them in software. If a karate student wants to learn this particular move, we use the software with an encoded temporal pattern to drive smart bulbs or another source of light while the student is practicing this move. The result is accelerated learning.
Example 3
(62) A person is reading a book, and during the course of the reading, brain activity, including electrical or magnetic activity, and optionally other measurements, as acquired. The data is processed to determine the frequency and phase, and dynamic changes of brainwave activity, as well as the spatial location of emission. Based on a brain model, a set of non-invasive stimuli, which may include any and all senses, magnetic nerve or brain stimulation, ultrasound, etc., is devised for a subject who is to read or learn the same book. The subject is provided with the book to read, and the stimuli are presented to the subject synchronized with the progress through the book. Typically, the book is presented to the subject through an electronic reader device, such as a computer or computing pad, to assist in synchronization. The same electronic reader device may produce the temporal pattern of stimulation across the various stimulus modalities. The result is speed reading and improved comprehension and retention of the information.
(63) Other examples of skill domains that may be facilitated include learning foreign languages, math, sports or specialized skills.
(64) The method of the present invention can be used to accelerate learning of new information, new subjects or fine motor skills.
(65) In this description, several preferred embodiments were discussed. Persons skilled in the art will, undoubtedly, have other ideas as to how the systems and methods described herein may be used. It is understood that this broad invention is not limited to the embodiments discussed herein. Rather, the invention is limited only by the following claims.
(66) The aspects of the invention are intended to be separable and may be implemented in combination, sub-combination, and with various permutations of embodiments. Therefore, the various disclosure herein, including that which is represented by acknowledged prior art, may be combined, sub-combined and permuted in accordance with the teachings hereof, without departing from the spirit and scope of the invention.
(67) All references and information sources cited herein are expressly incorporated herein by reference in their entirety.
(68) Hereinafter, embodiments of the present disclosure will be described in detail with reference to the accompanying drawings so that the present disclosure may be readily implemented by those skilled in the art. However, it is to be noted that the present disclosure is not limited to the embodiments but can be embodied in various other ways. In drawings, parts irrelevant to the description are omitted for the simplicity of explanation, and like reference numerals denote like parts through the whole document.
(69) Through the whole document, the term “connected to” or “coupled to” that is used to designate a connection or coupling of one element to another element includes both a case that an element is “directly connected or coupled to” another element and a case that an element is “electronically connected or coupled to” another element via still another element. Further, it is to be understood that the term “comprises or includes” and/or “comprising or including” used in the document means that one or more other components, steps, operation and/or existence or addition of elements are not excluded in addition to the described components, steps, operation and/or elements unless context dictates otherwise.
(70) Through the whole document, the term “unit” or “module” includes a unit implemented by hardware or software and a unit implemented by both of them. One unit may be implemented by two or more pieces of hardware, and two or more units may be implemented by one piece of hardware.
(71) Other devices, apparatus, systems, methods, features and advantages of the invention will be or will become apparent to one with skill in the art upon examination of the following figures and detailed description. It is intended that all such additional systems, methods, features and advantages be included within this description, be within the scope of the invention, and be protected by the accompanying claims.