High-barrier biodegradable Doypack and preparation method therefor

Abstract

A high-barrier biodegradable Doypack and a preparation method therefor. The Doypack consists of two parts, a high-barrier biodegradable self-sealing strip and a five-layered composite high-barrier biodegradable Doypack body. The main base materials of the high-barrier biodegradable self-sealing strip are PLGA and PPC that have excellent barrier performance; and the five-layered composite high-barrier biodegradable Doypack body consists of single side glossy white Kraft paper, a bonding layer, a first barrier layer, a second barrier layer, and a heat-sealing layer, which are integrally formed by using a process combining four-layer co-extrusion and lamination. Compared to conventional non-degradable Doypacks, the high-barrier biodegradable Doypack is substantially equivalent in terms of the physical and mechanical performance and heat-sealing performance, but has a superior barrier performance, and is biodegradable.

Claims

1. A method of preparing a high-barrier biodegradable Doypack includes the following steps: process 1. prepare high-barrier biodegradable self-sealing strip (1.1) prepare the raw material(weight fractions): 5-10 parts of poly (lactide-co-glycolide) (PLGA), 60-70 parts of polypropylene carbonate (PPC), and 20-30 parts of Polybutylene succinate (PBS), 1 part of Poly (N-Propionylaziridine), 0.5 parts of o-Phthalic anhydride, 0.2 parts of erucylamide, 0.5 parts of nano-silicon dioxide, 0.3 parts of white mineral oil. (1.2) mix uniformly the PLGA, PPC, PBS, Poly (N-Propionylaziridine), o-Phthalic anhydride, erucylamide, nano-silicon dioxide, white mineral oil in step (1.1) and add them to the parallel twin screw extruder (commercially equipment, prior art), melt blending and air-cooled pelletizing to prepare high-barrier biodegradable self-sealing strip modified material. (1.3) the high-barrier biodegradable self-sealing strip modified material prepared in step (1.2) is added to a bone strip extruder (commercially available, prior art), melted, extruded, water-cooled and shaped, and made into a high-barrier Biodegradable self-sealing strips process 2: prepare five-layer composite high-barrier biodegradable film roll (2.1) PBAT, organic modified montmorillonite, hyperbranched polyester HyPer C181, and white oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the bonding layer modification material. (2.2) PGA, tributyl O-acetylcitrate, Polyvinyl acetate, and antioxidant 168 are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare a first barrier layer modified material. (2.3) PPC, maleic anhydride, antioxidant 1010, hyperbranched polyester HyPer C100, and white mineral oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare a second barrier layer modified material. (2.4) add the modified materials prepared in steps (2.1), (2.2), (2.3) and PBS separately to the four extruders of a four-layer coextrusion casting machine (commercially equipment, prior art); starts the four extruders in sequence; by adjusting the rotating speed of each extruder, four-layer coextruded cast film with different thickness for each layer can be prepared; the four-layer coextruded cast film is composed of a heat sealing layer, a second barrier layer, a first barrier layer and a bonding layer from top to bottom; after the melt flow is stable, it is coated on the single side glossy white kraft paper and the rough surface of the single side glossy white kraft paper is bonding with the bonding layer of the melt; after trimming, it is made into a five-layer composite high-barrier biodegradable film roll; the five-layer composite high-barrier biodegradable film is used to prepare the body of high-barrier biodegradable bag; from the outside to the inside, the five-layer composite high-barrier biodegradable film are: a printing layer, a bonding layer, a first barrier layer, a second barrier layer, and a heat seal layer. (3) the high-barrier biodegradable self-seal strip prepared in step (1.3) and the five-layer composite high-barrier biodegradable film roll prepared in step (2.4) are prepared into a high-barrier biodegradable Doypack by a bone-sticking three-side sealing bag making machine.

2. The method of claim 1, wherein the PLGA described in step (1.1), the repeating unit —OCH.sub.2CO— accounts for 80%-90%, the weight average molecular weight(MW) of PLGA is 100,000˜200,000.

3. The method of claim 1, wherein the bonding layer modified material described in step (2.1) with the raw material formula(weight fraction): 92 parts of Poly (butyleneadipate-co-terephthalate)(PBAT), 7 parts of organically modified montmorillonite, 1 part of hyperbranched polyester HyPer C181, 0.3 parts of white mineral oil.

4. The method of claim 1, wherein the first barrier modified material prepared in step (2.2) with the raw material formula(weight fraction): 90 parts of polyglycolide (PGA), 5 parts of tributyl O-acetylcitrate, 5 parts of Polyvinyl acetate, and 0.5 parts of antioxidant 168.

5. The method of claim 1, wherein the weight average molecular weight (MW) of PGA described in step (2.2) is 150,000˜300,000, and the residual amount of Glycolide is not more than 0.3 wt %.

6. The method of claim 1, wherein the second barrier layer modified material prepared in step (2.3) with the raw material formula(weight fraction): 100 parts of polypropylene carbonate(PPC), 0.5 parts of maleic anhydride, 0.3 parts of antioxidant 1010, and 0.5 parts of hyperbranched polyester HyPer C100, 0.3 parts of white mineral oil.

7. The method of claim 1, wherein in the coextruded cast film specified in step (2.4), the thickness of the bonding layer is 5-10 microns.

8. The method of claim 1, wherein in the coextruded cast film specified in step (2.4), the thickness of the first barrier layer is 20-40 microns.

9. The method of claim 1, wherein in the coextruded cast film specified in step (2.4), the thickness of the second barrier layer is 20-40 microns.

10. A high-barrier biodegradable Doypack prepared by the method according to claims 1, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

11. A high-barrier biodegradable Doypack prepared by the method according to claims 2, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

12. A high-barrier biodegradable Doypack prepared by the method according to claims 3, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

13. A high-barrier biodegradable Doypack prepared by the method according to claims 4, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

14. A high-barrier biodegradable Doypack prepared by the method according to claims 5, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

15. A high-barrier biodegradable Doypack prepared by the method according to claims 6, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

16. A high-barrier biodegradable Doypack prepared by the method according to claims 7, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

17. A high-barrier biodegradable Doypack prepared by the method according to claims 8, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

18. A high-barrier biodegradable Doypack prepared by the method according to claims 9, it is characterized in that it is composed of a high-barrier biodegradable self-seal strip and a five-layer composite high-barrier biodegradable Doypack body.

Description

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT

[0039] The following embodiment further illustrate the content of the present disclosure. In the embodiment, the size of the Doypack is designed to be 9×(14+3) cm, which is consistent with the product size of the comparative example.

Embodiment 1

[0040] (1) Mix 5 parts of PLGA (repeat unit —OCH.sub.2CO— accounts for 80%, Mw 100000), 70 parts of PPC, 25 parts of PBS, 1 part of Poly (N-Propionyl aziridine), 0.5 part of o-Phthalic anhydride, 0.2 part of Erucylamide, 0.5 part of nano-silicon dioxide, 0.3 part of white mineral oil uniformly and add them to the parallel twin screw extruder, melt blending and air-cooled pelletizing to prepare high-barrier biodegradable self-sealing strip modified material.

[0041] (2) The high-barrier biodegradable self-sealing strip modified material prepared in step (1) is added to the bone strip extruder melted, extruded, water-cooled and shaped, and made into a high-barrier Biodegradable self-sealing strips.

[0042] (3) 92 parts of PBAT, 7 parts of organic modified montmorillonite, 1 part of hyperbranched polyester HyPer C181, and 0.3 parts of white oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the bonding layer modification material.

[0043] (4) 90 parts of PGA (Mw is 150000, the residual amount of Glycolide is 0.15 wt %), 5 parts of tributyl O-acetylcitrate, 5 parts of Polyvinyl acetate, and 0.5 part of antioxidant 168 are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the first barrier layer modified material.

[0044] (5) 100 parts of PPC, 0.5 parts of maleic anhydride, 0.3 parts of antioxidant 1010, 0.5 parts of hyperbranched polyester HyPerC100, and 0.3 parts of white mineral oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the second barrier layer modified material.

[0045] (6) Add the modified materials prepared in steps (3),(4),(5) and PBS separately to the four extruders of a four-layer coextrusion casting machine, and start the four extruders in sequence. By adjusting the rotating speed of each extruder, four-layer coextruded cast film with different thickness for each layer can be prepared: thickness of the bonding layer is 5 microns, thickness of the first barrier layer is 20 microns, thickness of the second barrier layer is 40 microns, thickness of the heat-sealing layer is 10 microns. From top to bottom, the four-layer coextruded cast film is the heat-sealing layer, the second barrier layer, the first barrier layer, and the bonding layer. After the melt flow is stable, it is coated on the single side glossy white kraft paper and the rough surface of the single side glossy white kraft paper is in contact with the bonding layer of the melt. After trimming, it is made into a five-layer composite high-barrier biodegradable film roll which the thickness is 140 microns.

[0046] (7) The high-barrier biodegradable self-seal strip prepared in step (2) and the five-layer composite high-barrier biodegradable film roll prepared in step (6) are prepared into a high-barrier biodegradable Doypack by a bone-sticking three-side sealing bag making machine. The size of the Doypack is 9×(14+3)cm.

Embodiment 2

[0047] (1) Mix 10 parts of PLGA (repeat unit —OCH.sub.2CO— accounts for 90%, Mw is 200,000), 60 parts of PPC, 30 parts of PBS, 1 part of Poly (N-Propionyl aziridine), 0.5 parts of o-Phthalic anhydride, 0.2 part of Erucylamide, 0.5 part of nano-silicon dioxide, 0.3 part of white mineral oil uniformly and add them to the parallel twin screw extruder, melt blending and air-cooled pelletizing to prepare high-barrier biodegradable self-sealing strip modified material.

[0048] (2) The high-barrier biodegradable self-sealing strip modified material prepared in step (1) is added to the bone strip extruder melted, extruded, water-cooled and shaped, and made into a high-barrier Biodegradable self-sealing strips.

[0049] (3) 92 parts of PBAT, 7 parts of organic modified montmorillonite, 1 part of hyperbranched polyester HyPer C181, and 0.3 parts of white oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the bonding layer modification material.

[0050] (4) 90 parts of PGA (Mw is 300,000, the residual amount of Glycolide is 0.1 wt %), 5 parts of tributyl O-acetylcitrate, 5 parts of Polyvinyl acetate, and 0.5 part of antioxidant 168 are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the first barrier layer modified material.

[0051] (5) 100 parts of PPC, 0.5 parts of maleic anhydride, 0.3 parts of antioxidant 1010, 0.5 parts of hyperbranched polyester HyPerC100, and 0.3 parts of white mineral oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the second barrier layer modified material.

[0052] (6) Add the modified materials prepared in steps (3),(4),(5) and PBS separately to the four extruders of a four-layer coextrusion casting machine, and start the four extruders in sequence. By adjusting the rotating speed of each extruder, four-layer coextruded cast film with different thickness for each layer can be prepared: thickness of the bonding layer is 5 microns, thickness of the first barrier layer is 20 microns, thickness of the second barrier layer is 40 microns, thickness of the heat-sealing layer is 10 microns. From top to bottom, the four-layer coextruded cast film is the heat-sealing layer, the second barrier layer, the first barrier layer, and the bonding layer. After the melt flow is stable, it is coated on the single side glossy white kraft paper and the rough surface of the single side glossy white kraft paper is in contact with the bonding layer of the melt. After trimming, it is made into a five-layer composite high-barrier biodegradable film roll which the thickness is 140 microns.

[0053] (7) The high-barrier biodegradable self-seal strip prepared in step (2) and the five-layer composite high-barrier biodegradable film roll prepared in step (6) are prepared into a high-barrier biodegradable Doypack by a bone-sticking three-side sealing bag making machine. The size of the Doypack is 9×(14+3)cm.

Embodiment 3

[0054] (1) Mix 10 parts of PLGA (repeat unit —OCH.sub.2CO— accounts for 90%, Mw is 200,000), 70 parts of PPC, 20 parts of PBS, 1 part of Poly (N-Propionyl aziridine), 0.5 parts of o-Phthalic anhydride, 0.2 part of Erucylamide, 0.5 part of nano-silicon dioxide, 0.3 part of white mineral oil uniformly and add them to the parallel twin screw extruder, melt blending and air-cooled pelletizing to prepare high-barrier biodegradable self-sealing strip modified material.

[0055] (2) The high-barrier biodegradable self-sealing strip modified material prepared in step (1) is added to the bone strip extruder melted, extruded, water-cooled and shaped, and made into a high-barrier Biodegradable self-sealing strips.

[0056] (3) 92 parts of PBAT, 7 parts of organic modified montmorillonite, 1 part of hyperbranched polyester HyPer C181, and 0.3 parts of white oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the bonding layer modification material.

[0057] (4) 90 parts of PGA (Mw is 300,000, the residual amount of Glycolide is 0.1 wt %), 5 parts of tributyl O-acetylcitrate, 5 parts of Polyvinyl acetate, and 0.5 part of antioxidant 168 are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the first barrier layer modified material.

[0058] (5) 100 parts of PPC, 0.5 parts of maleic anhydride, 0.3 parts of antioxidant 1010, 0.5 parts of hyperbranched polyester HyPerC100, and 0.3 parts of white mineral oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the second barrier layer modified material.

[0059] (6) Add the modified materials prepared in steps (3),(4),(5) and PBS separately to the four extruders of a four-layer coextrusion casting machine, and start the four extruders in sequence. By adjusting the rotating speed of each extruder, four-layer coextruded cast film with different thickness for each layer can be prepared: thickness of the bonding layer is 10 microns, thickness of the first barrier layer is 30 microns, thickness of the second barrier layer is 30 microns, thickness of the heat-sealing layer is 5 microns. From top to bottom, the four-layer coextruded cast film is the heat-sealing layer, the second barrier layer, the first barrier layer, and the bonding layer. After the melt flow is stable, it is coated on the single side glossy white kraft paper so that the rough surface of the single side glossy white kraft paper is in contact with the bonding layer of the melt. After trimming, it is made into a five-layer composite high-barrier biodegradable film roll which the thickness is 140 microns.

[0060] (7) The high-barrier biodegradable self-seal strip prepared in step (2) and the five-layer composite high-barrier biodegradable film roll prepared in step (6) are prepared into a high-barrier biodegradable Doypack by a bone-sticking three-side sealing bag making machine. The size of the Doypack is 9×(14+3)cm.

Embodiment 4

[0061] (1) Mix 10 parts of PLGA (repeat unit —OCH.sub.2CO— accounts for 90%, Mw is 200,000), 70 parts of PPC, 20 parts of PBS, 1 part of Poly (N-Propionyl aziridine), 0.5 parts of o-Phthalic anhydride, 0.2 part of Erucylamide, 0.5 part of nano-silicon dioxide, 0.3 part of white mineral oil uniformly and add them to the parallel twin screw extruder, melt blending and air-cooled pelletizing to prepare high-barrier biodegradable self-sealing strip modified material.

[0062] (2) The high-barrier biodegradable self-sealing strip modified material prepared in step (1) is added to the bone strip extruder melted, extruded, water-cooled and shaped, and made into a high-barrier Biodegradable self-sealing strips.

[0063] (3) 92 parts of PBAT, 7 parts of organic modified montmorillonite, 1 part of hyperbranched polyester HyPer C181, and 0.3 parts of white oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the bonding layer modification material.

[0064] (4) 90 parts of PGA (Mw is 300,000, the residual amount of Glycolide is 0.1 wt %), 5 parts of tributyl O-acetylcitrate, 5 parts of Polyvinyl acetate, and 0.5 part of antioxidant 168 are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the first barrier layer modified material.

[0065] (5) 100 parts of PPC, 0.5 parts of maleic anhydride, 0.3 parts of antioxidant 1010, 0.5 parts of hyperbranched polyester HyPerC100, and 0.3 parts of white mineral oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the second barrier layer modified material.

[0066] (6) Add the modified materials prepared in steps (3),(4),(5) and PBS separately to the four extruders of a four-layer coextrusion casting machine, and start the four extruders in sequence. By adjusting the rotating speed of each extruder, four-layer coextruded cast film with different thickness for each layer can be prepared: thickness of the bonding layer is 10 microns, thickness of the first barrier layer is 40 microns, thickness of the second barrier layer is 20 microns, thickness of the heat-sealing layer is 5 microns. From top to bottom, the four-layer coextruded cast film is the heat-sealing layer, the second barrier layer, the first barrier layer, and the bonding layer. After the melt flow is stable, it is coated on the single side glossy white kraft paper and the rough surface of the single side glossy white kraft paper is in contact with the bonding layer of the melt. After trimming, it is made into a five-layer composite high-barrier biodegradable film roll which the thickness is 140 microns.

[0067] (7) The high-barrier biodegradable self-seal strip prepared in step (2) and the five-layer composite high-barrier biodegradable film roll prepared in step (6) are prepared into a high-barrier biodegradable Doypack by a bone-sticking three-side sealing bag making machine. The size of the Doypack is 9×(14+3)cm.

Comparative Experiment 1

[0068] In this embodiment, the first barrier layer and the second barrier layer are omitted from the five-layer composite high-barrier biodegradable film roll prepared, and are used for performance comparison with the five-layer composite Doypack prepared by the present disclosure.

[0069] (1) Mix 10 parts of PLGA (repeat unit —OCH.sub.2CO— accounts for 90%, Mw is 200,000), 70 parts of PPC, 20 parts of PBS, 1 part of Poly (N-Propionyl aziridine), 0.5 parts of o-Phthalic anhydride, 0.2 part of Erucylamide, 0.5 part of nano-silicon dioxide, 0.3 part of white mineral oil uniformly and add them to the parallel twin screw extruder, melt blending and air-cooled pelletizing to prepare high-barrier biodegradable self-sealing strip modified material.

[0070] (2) The high-barrier biodegradable self-sealing strip modified material prepared in step (1) is added to the bone strip extruder melted, extruded, water-cooled and shaped, and made into a high-barrier Biodegradable self-sealing strips.

[0071] (3) 92 parts of PBAT, 7 parts of organic modified montmorillonite, 1 part of hyperbranched polyester HyPer C181, and 0.3 parts of white oil are mixed uniformly and then added to the parallel twin screw extruder, melted, blended and air-cooled pelletizing to prepare the bonding layer modification material.

[0072] (4) Add the modified materials prepared in steps (3) and PBS separately to the two extruders of a two-layer coextrusion casting machine, and start the two extruders in sequence. By adjusting the rotating speed of each extruder, two-layer coextruded cast film with different thickness for each layer can be prepared: thickness of the bonding layer is 35 microns, thickness of the PBS layer is 40 microns. From top to bottom, the two-layer coextruded cast film is the heat-sealing layer and the bonding layer. After the melt flow is stable, it is coated on the single side glossy white kraft paper and the rough surface of the single side glossy white kraft paper is in contact with the bonding layer of the melt. After trimming, it is made into a three-layer composite high-barrier biodegradable film roll which the thickness is 140 microns.

[0073] (5) The high-barrier biodegradable self-seal strip prepared in step (2) and the three-layer composite high-barrier biodegradable film roll prepared in step (4) are prepared into a high-barrier biodegradable Doypack by a bone-sticking three-side sealing bag making machine. The size of the Doypack is 9×(14+3)cm.

Comparative Experiment 2

[0074] At present, the bag body of the seal type Doypack that are mass-produced and used on the market, according to the product description, is made of kraft paper+PET+CPP three-layer composite material. It is a non-degradable material. For comparison experiments, traditional seal type Doypack was purchased. The specific product model is: the bag body is made of kraft paper+PET+CPP three-layer composite material, the thickness of the single layer of the bag body is 140 microns, and the size of the Doypack is 9×(14+3)cm.

Embodiment 5

[0075] This embodiment is to evaluate the physical and mechanical properties (including tensile break stress and heat seal strength) of the body material of the Doypack prepared in embodiment 1 to 4 and Comparative Experiment 2. The physical and mechanical properties are tested on a universal tensile testing machine (CMT-4304, made by Nss(Shenzhen) Laboratory Equipment Co., LTD). The tensile break stress is tested in accordance with GB/T1040.3-2006, the test speed is 250 mm/min, and the heat seal strength is in accordance with QB/T2358-1998, the test speed is 300 mm/min, and the test results are shown in Table 1.

TABLE-US-00001 TABLE 1 Physical and mechanical properties of different Doypack body materials Tensile Break Stress/N Heat seal strength Doypack type Lateral Vertical (N/15 mm) Embodiment 1 48.57 46.79 32.74 Embodiment 2 49.34 50.21 33.57 Embodiment 3 56.49 55.37 27.37 Embodiment 4 54.31 54.22 28.45 Comparative 51.66 50.84 30.31 experiment 2

[0076] From the embodiments in Table 1 and the comparative experiment, it can be concluded that the high barrier biodegradable Doypack material provided by the present disclosure has the same physical and mechanical properties as the traditional commercial Doypack. When the thickness of the first barrier layer reaches 30 microns, it has better tensile break stress performance than traditional commercial Doypack material. The heat seal strength of the high-barrier biodegradable Doypack material of the present disclosure is basically equivalent to that of traditional Doypack material.

Embodiment 6

[0077] This embodiment aims to evaluate the barrier properties (including water vapor transmission and oxygen transmission tests) of the Doypack body materials prepared in Embodiment 1 to 4 and Comparative Experiments 1 to 2 and the sealing performance of the Doypack.

[0078] The water vapor transmission rate (WVT) is tested on the W3/031 Water Vapor Transmission Rate Tester(produced by Labthink Instruments Co., Ltd.) in accordance with GB/T1037-1988. The experimental conditions are: temperature 38±0.6° C., relative humidity 90%±2%, and test area 33 cm.sup.2.

[0079] The Oxygen transmission rate (O.sub.2TR) is tested on sealing tester in accordance with GB/T1038-2000 in a VAC-V2 Gas Permeability Tester(produced by Labthink Instruments Co., Ltd.). The experimental conditions are: temperature 23±2° C., relative humidity 0%.

[0080] The sealing performance is tested on is in accordance with GB/T15171-1994, Method 2A. The test results are shown in Table 2.

TABLE-US-00002 TABLE 2 Barrier performance and sealing performance of different Doypacks Sealing WVT O.sub.2TR Performance Film type (g/m.sup.2*24 h) (cm.sup.3/m.sup.2*24 h*0.1 MPa) (50 kPa) Embodiment 1 9.2584 1.2373 no-leakage Embodiment 2 8.2465 0.9526 no-leakage Embodiment 3 5.3132 0.6118 no-leakage Embodiment 4 2.6992 0.3279 no-leakage Comparative 265.6 1260.6271 no-leakage Experiment 1 Comparative 4.3128 29.3564 no-leakage Experiment 2

[0081] From the data in Table 2, it can be concluded that the oxygen permeability of the high-barrier biodegradable Doypack made by the present disclosure is significantly lower than that of the traditional Doypack. When the thickness of the first barrier layer reaches 40 microns, the water vapor transmission rate of the high-barrier biodegradable Doypack is also lower than that of the traditional Doypack. In general, the barrier performance of the high-barrier biodegradable Doypack provided by the present disclosure is better than that of the traditional Doypack. In addition, the test results of the sealing performance show that the high barrier biodegradable Doypack has good sealing performance.

[0082] The PLGA and PGA used in the present embodiment are produced by our company. Other raw materials such as PBAT, PPC, PBS, Poly (N-Propionyl aziridine), maleic anhydride, o-Phthalic anhydride, Erucylamide, nano-silicon dioxide, White mineral oil, single gloss white kraft paper, Organic modified montmorillonite, hyperbranched polyester HyPer C181, hyperbranched polyester HyPer C100, tributyl O-acetylcitrate, Polyvinyl acetate, antioxidant 168, antioxidant 1010 can be purchased directly from the market.