In certain embodiments, an ophthalmic laser surgical system for imaging and treating a target in an eye includes a laser device, imaging system, and computer. The laser device directs the focus of a laser beam towards an intended location (x0, y0, z0) of the target to yield a cavitation bubble in the vitreous. The imaging system directs imaging beams towards the target, receives the imaging beams reflected from the eye, generates an image of the cavitation bubble from the reflected imaging beams, and measures an actual location (x, y, z) of the cavitation bubble according to the image. The computer determines an error vector that describes an error between the intended location and the actual location, determines a correction vector to compensate for the error, and instructs the laser device to use the correction vector to direct the laser beam towards the target to treat the target.

An ophthalmological device for refractive correction of a cornea comprises a laser source, a focusing optical module, a scanner system and an electronic circuit. The electronic circuit is configured to control the scanner system to move the focal spot of the pulsed laser beam generated by the laser source to generate a first part of a void volume ablating cornea tissue inside the first part of the void volume, and to generate a separated second part of the void volume by separating the second part of the void volume as piece of cornea tissue to be removed from the void volume through an incision in the cornea, whereby at least a part of the separated second part is separated from the cornea by the ablated first part.

The invention relates to a device for measuring an optical penetration that is triggered in a tissue underneath the tissue surface by means of therapeutic laser radiation which a laser-surgical device concentrates in a treatment focus located in said tissue. The inventive device is provided with a detection beam path comprising a lens system which couples radiation emanating from the tissue underneath the tissue surface into the detection beam path. A detector device generating a detection signal which indicates the spatial dimension and/or position of the optical penetration in the tissue is arranged downstream of the detection beam path.

A focusing optical system for a UVL-LVC system with a UV laser source and a scanning system that focuses a laser in a focal field and a lens assembly with a convergent focal field. The invention further includes a planning unit that generates planning data for a UVL-LNC system with a UV laser source, a scanning system, a focusing optical system, and a control unit for controlling the UVL-LVC system while taking into consideration planning data, wherein the planning unit takes into consideration geometry losses, Fresnel losses, and/or a spatial extension of laser radiation on a working surface while calculating the planning data, and the planning unit has an interface that provides the planning data. Finally, the invention includes a UVL-LVC system with a UV laser source, a scanning system, a focusing optical system according to the invention, a planning unit according to the invention, and a control unit.

A method for aligning a system for laser-based ametropia correction relative to a patient's eye to be treated is disclosed. Predefined pre-operative measurement data which characterize at least predetermined structures of the patient's eye is provided. The predetermined structures include a part of the patient's eye to be treated. In addition, the method includes measuring at least one part of the predetermined structures of the patient's eye using an OCT system immediately before and/or during treatment for ametropia correction of the patient's eye and providing OCT measurement data, and comparing the OCT measurement data and the predefined pre-operative measurement data and preparing comparative data. The method also includes ascertaining a position and/or orientation of the part of the patient's eye to be treated relative to the system and aligning the system relative to the patient's eye using the ascertained position and/or orientation of the part of the patient's eye.

An ophthalmic laser apparatus comprises a laser light source; a light guide device, configured to guide a laser beam generated from the laser light source; a support bracket, configured to support a patient's head for the patient's eye to be perpendicular to a horizontal plane; a positioning device to acquire data related to a position of the patient's eye; a laser beam projector, the laser beam projector being movable to be aligned with the patient's eye and projecting the laser beam from the light guide device; a moving stand, configured to move the positioning device and the laser beam projector along an X direction, a Y direction, and/or a Z direction; and a controller, configured to control the laser light source to irradiate the laser beam and to control the laser beam projector to project the laser beam toward the patient's eye.

A method of treating a subject having glaucoma comprises performing excimer laser trabeculostomy (ELT) on a subject having glaucoma and having previously undergone a failed treatment or a treatment that has been rendered ineffective by progression of the disease. In some examples, the failed treatment is a non-surgical treatment comprising administering medicated eye drops. In some examples, the failed treatment is a laser treatment or surgical treatment, such as a trabeculoplasty, iridotomy, iridectomy, trabeculectomy, trabeculotomy, goniotomy, surgical insertion of a shunt or implant, deep sclerectomy, viscocanalostomy, or a combination thereof.

Rather than rely solely upon pupillary occlusion or tracking of eye movement to protect the fundus from accidental exposure to electromagnetic radiation, the present invention also utilizes an electromagnetic radiation pathway with a profile such that the energy density at the iris is greater than the energy density at the posterior portion of the eye. This disparity in energy density allows for efficacy at the anterior iris treatment site, without injury to the fundus.

A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

A method of preventing capsular opacification and fibrosis utilizing an accommodative intraocular lens implant, which includes the steps of removing a cortex and nucleus of a natural lens containing a cataract from a lens capsule of an eye of a patient; applying a photosensitizer inside the lens capsule so that the photosensitizer permeates a portion of the lens capsule, the photosensitizer facilitating cross-linking of the tissue in the portion of the lens capsule; irradiating the portion of the lens capsule so as to activate cross-linkers in the tissue in the portion of the lens capsule, thereby damaging the remaining lens epithelial cells in the lens capsule with the irradiated light so as to prevent capsular opacification and fibrosis; and injecting a transparent polymer into the lens capsule of the eye in order to form an accommodative intraocular lens for replacing the cortex and nucleus of the natural lens.