A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity.

A bilateral hearing implant system has a left side and a right side. There is an interaural time delay (ITD) processing module on each side that adjusts ITD characteristics of the stimulation signals based on defined groups of stimulation channels that include: i. an apical channel group on each side corresponding to a lowest range of audio frequencies up to a common apical channel group upper frequency limit, wherein a common number of one or more stimulation channels is assigned to each apical channel group, and wherein corresponding apical channel group stimulation channels on each side have matching bands of audio frequencies, and ii. one or more basal channel groups on each side corresponding to higher range audio frequencies above the apical channel group upper frequency limit.

A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity.

Semi-autonomous vehicle apparatus which is controlled by a plurality of control sources includes a vehicle which may function autonomously and apparatus for control of the vehicle by either an onboard driver or a driver not situated onboard. The vehicle may also be controlled by an off-vehicle computational device. Hierarchy setting apparatus determines which one or combination of the possible control entities take priority. Persons using the apparatus are identified by either a password or, preferably by providing identification based on a biologic feature. Management of impaired vehicle operators is provided for.

The implant comprises a tubular body housing an energy harvesting module adapted to convert external stresses applied to the implant into electrical energy, and a rechargeable battery adapted to be charged by the energy harvesting module. During the storage, an external source physically separated from the implant is coupled to the implant rechargeable battery to maintain a minimum battery charge level. An interface circuit of the implant couples surface electrodes to the battery, with switching between: i) a transport and storage configuration where the electrodes are connected to the external source to receive from the latter a battery charging energy and/or to exchange communication signals with the outside through the wire link of the coupling; and ii) a functional configuration in which the surface electrodes are decoupled from the external source after the implant has been implanted. The implant further comprises a data transmitter circuit adapted, in the transport and storage configuration, to send communication signals, via the surface electrodes, on the link coupling to the external source, and/or a data receiver circuit adapted, in the transport and storage configuration, to receive, via the surface electrodes, communication signals transmitted on the link coupling to the external source.

A neural stimulator system which generates stimulation from an implantable stimulator circuit which generates stimulation outputs which mimic biological signals. The user/operator can select stimulation generated from recorded waveforms, or by selecting the characteristics for generating stimulation based on randomized inter-pulse-intervals (IPI). A control unit controls the operation of the implantable stimulator circuit, and receives sets of stimulation parameters based on user input from a user input device executing application specific programming.

A bridge device includes a housing, a plurality of electrodes exposed outside of the housing such that at least two of the plurality of electrodes can be concurrently placed in contact with a patient's skin. A controller is disposed within the housing. A first communications module is operably coupled to the controller and to the at least two of the plurality of electrodes. The first communications module is configured to allow the controller to communicate with an implantable medical device via at least two of the plurality of electrodes using conducted communication. A second communications module is operably coupled to the controller and is configured to allow the controller to communicate with a remote device external to the patient.

Wirelessly powered implantable pulse generators (IPG) are described. In an embodiment, a wirelessly powered stimulator, includes an implantable pulse generator (IPG), including: an Rx antenna that receives a radio frequency (RF) signal from an external Tx antenna; a rectifier; an energy storage capacitor C.sub.STOR, where the RF signal coupled to the Rx antenna is rectified by the rectifier to generate VDD and charges the C.sub.STOR; a demodulator; an output voltage regulator that generates a stable voltage to activate the demodulator; and where the demodulator outputs a stimulation that releases the energy stored in the C.sub.STOR on an electrode based on detecting amplitude modulation in the received RF signal; and a Tx antenna that generates the RF signal that wirelessly powers the IPG and that controls timing of output stimulations of the IPG, where amplitude modulation is applied to the RF signal to control the timing of the output stimulations.

An advertising algorithm is disclosed which operates in an Implantable Medical Device (IMD) to adjust an interval at which the IMD will transmit advertising data packets to an external device able to connect with the IMD. When a communication session between the IMD and an external device is terminated, the advertising algorithm will issue advertising data packets at a higher rate for a set duration. This will allow the external device to connect more quickly with the IMD in a next communication session. After the set duration, when it may be assumed that the external device is less likely to connect with the IMD, the algorithm reduces that rate at which advertising data packets are issued, which saves power in the IMD.

Provided herein are methods of treating a patient comprising providing a medical apparatus comprising an external system and an implantable system, implanting the implantable system, and delivering at least one of power or data to the implantable system with the external system. The external system comprises: at least one external antenna configured to transmit a first transmission signal to the implantable system; an external transmitter configured to drive the at least one external antenna; an external power supply; and an external controller. The implantable system comprises: at least one implantable antenna configured to receive the first transmission signal from the first external device; an implantable receiver; at least one implantable functional element configured to interface with the patient; an implantable controller; an implantable energy storage assembly; and an implantable housing surrounding at least the implantable controller and the implantable receiver. Medical apparatus are also provided.