This application is generally related to systems and methods for providing a medical therapy to a patient by tracking patient activity and adjusting medical therapy based on occurrence of different types of activities performed by the patient including user indicated activities inputted from an icon driven user interface of an external patient controller device.

An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine an R-wave of the cardiac signal and determine whether the R-wave is noisy. Based on the R-wave being noisy, the processing circuitry is configured to determine whether the cardiac signal around a determined T-wave is noisy. Based on the cardiac signal around the determined T-wave not being noisy, the processing circuitry is configured to determine a QT interval or a corrected QT interval based on the determined T-wave and the determined R-wave.

A variety of dispatcher user interfaces, communications architectures, methods, apparatus, APIs and protocols are described that can help facilitate the integration of volunteer responder networks into the workflows of PSAP dispatchers. In one aspect, a dispatcher user interface facilitates activation of the volunteer responder network, as well as tracking and/or communicating notes to medical devices such as AEDs in the responder network that have accepted an incident.

Devices and methods for manipulating devices such as micro-scale devices are provided. The devices can include a tether of various materials surrounded by a stiff body. The tether interfaces with microscale devices to draw them against the stiff body, holding the microscale devices in a locked position for insertion into or extraction out of tissue. The tensional hook and stiff body are configurable in a multitude of positions and geometries to provide increased engagement. Such configurations allow for a range of implantation and extraction surgical procedures for the device within research and clinical settings.

A system for generating an alert for a systemic infection of a patient comprises an implantable medical device configured to measure at least one physiological parameter, a remote monitoring system configured to receive information from the implantable medical device, and an information system configured to communicate with said remote monitoring system. At least one of the implantable medical device, the remote monitoring system and the information system is configured to analyze information relating to said at least one physiological parameter to generate an alert signal for a systemic infection of the patient based on a state of the at least one physiological parameter, wherein at least one of the implantable medical device, the remote monitoring system and the information system is further configured to generate an alert message to be provided to a specified destination based on said alert signal.

Methods, implantable devices, and systems for treating a cancer or inhibiting cancer growth or recurrence in a subject are described herein. Such methods can include electrically stimulating a thoracic splanchnic nerve (such as a greater splanchnic nerve) of the subject with a plurality of electrical pulses emitted from one or more electrodes m electrical communication with the splanchnic nerve, wherein the plurality of electrical pulses triggers one or more action potentials in the splanchnic nerve to increase circulating natural killer (NK) cells in the subject. An implantable device may include one or more electrodes configured to be in electrical communication with a thoracic splanchnic nerve of a subject with cancer, and be configured to operate the one or more electrodes to electrically stimulate the splanchnic nerve with a plurality of electrical pulses that triggers one or more action potentials in the splanchnic nerve that increase circulating NK cells.

A bone growth stimulator includes an antenna configured to receive electromagnetic signals in a radio frequency band, and a controller having a power source including a supercapacitor electrically connected to the antenna. The supercapacitor stores a charge in accordance with the electromagnetic signals received by the antenna. The bone growth stimulator further includes a cathode extending from the controller to a desired location of bone growth and an anode electrically connected to the power source and extending from the controller. Electrical energy travelling from the anode to the cathode stimulates bone growth in a patient.

The invention relates to a telemetry communication system for an implantable medical device (1) comprising a radiofrequency transceiver, comprising: a remote controller (2) adapted to be used by a patient into whom said medical device (1) is implanted, said remote controller comprising a radiofrequency transceiver configured to communicate with said implantable medical device in a first frequency band (RF1), the transceiver of the remote controller (2) being paired with the transceiver of the implantable medical device (1), a programming device (3) said implantable medical device adapted to be used by a practitioner, comprising a user interface (30), and configured to communicate with the remote controller (2) through a wire connection or a wireless connection in a second frequency band (RF2) different from the first frequency band, the programming device (3) being configured to, when said connection is established between the remote controller (2) and the programming device (3), establish a communication between the implantable medical device and the programming device through the remote controller.

An implantable medical device, comprises a primary communication component for establishing a communication connection with an external communication arrangement outside of a patient. The external communication arrangement is a mesh network comprising a multiplicity of nodes, wherein the primary communication component is configured to act as an additional node in the mesh network for exchanging data with at least one of the multiplicity of nodes of the mesh network, and wherein at least one of the nodes of the mesh network is formed by a lighting device, which regularly are present within an environment, in which the patient regularly stays.

Devices and methods for manipulating devices such as micro-scale devices are provided. The devices can include a tether of various materials surrounded by a stiff body. The tether interfaces with microscale devices to draw them against the stiff body, holding the microscale devices in a locked position for insertion into or extraction out of tissue. The tensional hook and stiff body are configurable in a multitude of positions and geometries to provide increased engagement. Such configurations allow for a range of implantation and extraction surgical procedures for the device within research and clinical settings.