The present disclosure is directed to fatty-acid glycerol ester derivative compounds containing a targeting bisphosphonate group. The disclosure further includes pharmaceutical or biomedical compositions comprising these compounds, and methods of using these compounds and compositions forming microbubbles. The microbubbles have affinity for metal-containing, especially calcium-containing, bodies and/or biological targets. In certain embodiments, these compositions are useful for providing targeted placement of microbubbles capable of cavitation on application of high frequency energy.

This disclosure provides a composition comprising a mixture of molecules of Formula (I): {RO-[CH(CH.sub.3)CH.sub.2O)]b[CH.sub.2-CH.sub.2O]a}.sub.mP(=O)(O.sup.−X.sup.+).sub.n(I), wherein R is chosen from linear or branched C.sub.10-C.sub.18 alkyl or alkenyl groups; a is 0 to 50, b is 0-30, and a+b >0; X.sup.+ is potassium, triethanolamine, or H, and m and n are each equal to 1 or 2, such that when m=1 then n=2, and when m=2 then n=1. Moreover, in the mixture some of the molecules have m=1 and n=2 and some of the molecules have m=2 and n=1, wherein the mole ratio of compounds where m=1 to compounds where m=2 is of from 1:1 to 3:1.

The invention concerns a polycondensate containing (I) at least a structural unit, which is an aromatic moiety bearing a polyether side chain comprising 9 to 41 alkylene glycol units, (II) at least a structural unit, which is an aromatic moiety bearing at least one phosphoric acid ester group and (III) at least a methylene unit (—CH.sub.2—), the polycondensate having a polycondensation degree of 10 to 75. Also concerned are building material mixtures containing said polycondensates and the use as dispersant for inorganic binders.

An article comprising a flexible polymer substrate having two major surfaces, a surface layer comprising metal, metal oxide, silicon flexible polymer substrate; and a coating disposed on at least one surface layer, wherein the coating comprises a fluorinated polymer bonded to the surface layer; wherein the fluorinated polymer has the following general formula (I), where n=6 to 120; and where n=6 to 120; and where m=1 to 25 (R1); (R2); or where m=1 to 25 (R3).

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The present invention provides compositions and methods for delivery of therapeutic agents across an barrier. The compositions include a therapeutic agent (e.g., antimicrobial agent, antibiotic, or anesthetic agent), a permeation enhancer which increases the flux of the therapeutic agent across the barrier, and a matrix forming agent. The matrix forming agent forms a gel at a suitable gelation temperature and rheological properties for use in drug delivery, and in some cases, the gelation temperature and rheological properties are not significantly changed from those of the composition without the permeation enhancer. The invention also provides a matrix forming agent and compositions thereof. Such compositions are particularly useful in the treatment of otitis media. Methods of treatment, methods of delivery, and kits for the compositions described herein are also provided.

A graffiti-repellant article comprising a substrate having a surface comprising metal, metal oxide, silicon oxide, or combinations thereof; and an impervious coating disposed on said surface, wherein the impervious coating comprises a fluorinated polymer bonded to the surface layer; wherein the fluorinated polymer has the following general formula (I) where n=6 to 120.

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Disclosed are oral care compositions of novel phosphono-phosphate and anionic group containing polymer compositions that have targeted uses with divalent cations and surfaces having divalent cations. These compounds can be used to deliver anionic character to surfaces such as calcium hydroxyapatite for use in oral care applications.

Disclosed are oral care compositions of novel phosphono-phosphate and anionic group containing polymer compositions that have targeted uses with divalent cations and surfaces having divalent cations. These compounds can be used to deliver anionic character to surfaces such as calcium hydroxyapatite for use in oral care applications.

The invention relates to compositions containing compounds of formula (I), formula (II), or mixtures thereof, in which n is an integer greater than or equal to 1, R.sup.1, an aliphatic, linear or branched hydrocarbon group having 1 to 10 carbon atoms, a hydrogen atom, the structural unit —O—X, or the structural unit —CH.sub.2—O—X, X corresponds to formula (III), in which a is an integer from 2 to 6, b is an integer from 0 to 3, c is an integer from 20 to 28, m is 1 or 2, R.sup.2 is an aliphatic, linear or branched hydrocarbon group having 1 to 10 carbon atoms, Y is hydrogen, —SO.sub.3M, —SO.sub.2M, —PO.sub.3M.sub.2, or —CH.sub.2COOM, and M is a cation. The compounds of formula (I), of formula (II), or mixtures thereof are preferably suitable to act as a dispersing agent. ##STR00001##

A polymer electrolyte including a poly(ethylene oxide) (PEO) containing polymer; and a lithium salt, wherein a terminal of the poly(ethylene oxide) containing polymer is substituted with a sulfur compound functional group, a nitrogen compound functional group or a phosphorus compound functional group, and a method for preparing the same and a battery containing the same.