G01N2001/2223

Electrostatic Precipitation-Based Sampler for Bioaerosol Monitoring

A compact, portable, low-cost electrostatic bioaerosol sampler device is provided for collection of aerosolized biological and non-biological particles. The device may be used for long-term, large-scale deployment. With a low-pressure design, the device can sample a high flowrate of 10 lit/min with a low-power fan. The device collects dust particles with a nominal size range of 1-10 μm, with an efficiency of >60%. The device may include aerosol sensing components, a particle ionizer, and an electrostatic precipitator. A removable cassette includes a ground plate for collection of ionized particles and a high voltage plate opposite the ground plate. A divider may be included beneath the ionizer to facilitate separation of collected particles by size on the ground plate.

SYSTEMS AND METHODS OF RAPID AND AUTONOMOUS DETECTION OF AEROSOL PARTICLES

Disclosed are systems and methods to provide rapid and autonomous detection of analyte particles in gas and liquid samples. Disclosed are methods and devices for identifying biological aerosol analytes using MALDI-MS and chemical aerosol analytes using LDI and MALDI-MS using time-of-flight mass spectrometry (TOFMS).

Cell population analysis

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

SYSTEM AND METHOD OF BIOCHEMICAL MOLECULE SYNTHESIS AND DETECTION IN A POINT OF COLLECTION SETTING
20230027503 · 2023-01-26 · ·

A system for nucleic acid amplification is to synthesize amplified target nucleic acids or determine the presence of target nucleic acid. The mobile device of the system implements with an interface for controlling the reaction as well as optionally recording or delivering the reaction results or protocols to a cloud for sharing. In addition, current invention also discloses an airborne molecule detector integrating both air sampler and biochemical analysis component. The device can monitor the bioaerosols on real time. The reaction product can be used for nucleic acid sequencing as well. Furthermore, a pH test strip is used to replace a halochromic agent in a reaction mix for determining the nucleic acid amplification.

TEST CHAMBER APPARATUS FOR ASSESSING FILTER MEDIA

An apparatus includes (i) a test chamber having an inlet and an outlet; (ii) an introduction system configured to introduce a test pollutant into the test chamber such that the test pollutant is entrained in air flowing from the inlet to the outlet; (iii) a support configured to retain the test article, wherein the support defines a passageway downstream of a location of the test article such that air flowing from the inlet to the outlet passes through the filter medium prior to entering the passageway; (iv) an air flow apparatus configured to draw air from within the test chamber through the passageway and the outlet; and (v) a respiratory conditions simulation system configured to simulate an aspect of respiration, an external environment simulation system configured to simulate an aspect of an external environment, or both the respiratory conditions simulation system and the external environment simulation system.

METHOD OF EVALUATING AEROSOL REMOVAL RATE BY STEAM CONDENSATION IN STEEL CONTAINMENT
20230228664 · 2023-07-20 ·

A method of evaluating the aerosol removal rate by steam condensation, comprising: establishing the aerosol removal rate evaluation facility to perform the aerosol gravity settling experiment without steam and the comprehensive aerosol removal experiment with steam, so as to obtain aerosol mass concentration and particle size distribution in the experiments without steam and with steam condition respectively as calculation parameters; and then obtaining, by calculation, the relationship between the aerosol gravity settling rate and the particle size, aerosol mass concentration removed only by the gravity mechanism in the comprehensive aerosol removal experiment, aerosol mass concentration removed by steam condensation mechanism in the comprehensive aerosol removal experiment, and the aerosol removal rate by steam condensation in the comprehensive aerosol removal experiment.

Self-propelled pathogen detection device, pathogen detection system, and control method

The present disclosure provides a self-propelled pathogen detection device in which a place where a pathogen is highly likely to be present in a space such as an inside of a facility is allowed to be configured preferentially to be a target region of detection. The self-propelled pathogen detection device according to the present disclosure comprises a housing; a detection part for detecting a pathogen; a movement mechanism for moving the housing; a position acquirement part for acquiring position information representing a current position of the housing in a space; and a control part which determines a target region in the space on the basis of traffic line information on a person in the space, and controls the movement mechanism to move the housing in the target region on the basis of the position information. The detection part detects the pathogen in the target region.

Condensation Countermeasures for Airborne Particle Detectors
20230024872 · 2023-01-26 ·

Condensation associated with the collection and identification of airborne particles is detected. Upon the detection, one or more condensation countermeasures are triggered to address the condensation.

Method for collecting particles from exhaled breath using a portable sampling device
11701030 · 2023-07-18 · ·

A portable handheld sampling device for collecting aerosol particles in a stream of exhaled breath provided with an inlet and an outlet, wherein the sampling device further comprises a housing and a collecting device holder removably arranged at least partially inside the housing, wherein the housing and the collecting device holder are arranged to guide the stream of exhaled breath through the device from the inlet to the outlet, wherein said collecting device holder comprises at least two cylindrical conduits arranged in parallel, each defining a flow path in fluid connection with the inlet, wherein a cylindrical collecting device is arranged in each conduit, the collecting device being adapted to collect the aerosol particles in the exhaled breath. A method for collecting aerosol particles in exhaled breath of a user using a portable handheld sampling device by means of a reopening breathing maneuver.

Dynamic Modification of Bioaerosol Detection with Genetic Identification
20230228652 · 2023-07-20 ·

A bioaerosol detector is operated in accordance with one or more first inputs. Operating the bioaerosol detector includes filtering pathogens from the air, extracting genetic material from the filtered pathogens, and analyzing the extracted genetic material to identify the filtered pathogens. While operating the bioaerosol detector in accordance with the one or more first inputs, a change is identified in an operating condition for the bioaerosol detector. In response, the bioaerosol detector is operated in accordance with one or more second inputs. At least one input of the one or more second inputs is distinct from a respective input of the one or more first inputs.