A biological component measurement apparatus includes an optical medium, a high thermal conductive film, an excitation light source, a probe light source, and a light position detector. The high thermal conductive film is higher in thermal conductivity than the optical medium, and is provided on a sample placement surface of the optical medium. The high thermal conductive film spreads heat generated from the sample irradiated with excitation light more in a first direction than in a second direction. The first direction is a traveling direction of probe light in plan view of the sample placement surface. The second direction is a direction orthogonal to the first direction in plan view of the sample placement surface.

According to the embodiment, a processing apparatus includes an arithmetic section. The arithmetic section is configured to calculate a refractive index distribution forming a light beam path based on an estimated output calculated by inputting light beam data indicating the light beam path to an estimation model, an updated output calculated based on the light beam data and the estimated output, and an evaluation index of the estimation model calculated from a ray equation independent of a time which the light beam path follows.

Methods, systems, and devices for wearing detection are described. A method may include directing light from a first light emitting element to a first light detecting element via an optical interface, at least one of the first light emitting element or the first light detecting element dedicated to detecting a level of surface contact at the optical interface. The method may include measuring, via the first light detecting element, an amount of escaped light which escaped the optical interface, where the amount of escaped light is indicative of the level of surface contact. The method may further include controlling an activation of a second light emitting element and a second light detecting element based on the level of surface contact, at least one of the second light emitting element or the second light detecting element dedicated to measuring a physiological phenomenon at a user of the wearable device.

A system includes a light source, a first lens, a second lens, a third lens, a beam splitter, a first image collection device, and a second image collection device. The first lens is configured to collimate a light beam and to direct the collimated light beam through a test sample. The beam splitter is configured to split the light beam from the test sample and to transmit a first portion of the light beam toward the second lens and reflect a second portion of the light beam toward the third lens. The first image collection device is positioned adjacent to a first obstruction and configured to record an obstructed first image formed by the first portion of the light beam. The second image collection device is positioned adjacent to a second obstruction and configured to record an obstructed second image formed by the second portion of the light beam.

A method and system is provided that measures plasma protein levels of whole blood while a plasma donor is connected to an apheresis machine. A refractometer associated with the apheresis machine is capable of receiving a portion of a disposable tubing set including an integrated cuvette and prism. The integrated cuvette of the disposable tubing set can be inserted into a receiving space of the refractometer associated with the apheresis machine such that the light source and the sensor are oriented relative to the prism and a sensing surface of the integrated cuvette in a precise alignment. Calibration of the refractometer is made using anticoagulant pumped through the disposable tubing set including the integrated cuvette and prism. Based on a light intensity associated with this calibration, whole blood is then measured to determine plasma protein levels and donor eligibility.

A method for determining an index-of-refraction profile of an optical object, which has a cylindrical surface and a cylinder longitudinal axis, said method comprising the following method steps: (a) scanning the cylindrical surface of the object at a plurality of scanning locations by means of optical beams; (b) capturing, by means of an optical detector, a location-dependent intensity distribution of the optical beams deflected in the optical object; (c) determining the angles of deflection of the zero-order beams for each scanning location from the captured intensity distribution, comprising eliminating beam intensities, and (d) calculating the index-of-refraction profile of the object on the basis of the angle-of-deflection distribution, wherein method steps (a) and (b) are carried out with light beams having at least two different wavelengths.

A method of analyzing a material (12) comprising at least one analyte, said method comprising a material status analyzing procedure (76), in which a present status of the material is analyzed, wherein based on a result of said material status analyzing procedure (76), at least one of a selection of analyte-characteristic-wavelengths used during an analyte measurement procedure (78), an absolute time or a relative time proportion of use of analyte-characteristic-wavelengths during said analyte measurement procedure (78), an individual excitation radiation intensity, or a relative weight given to the wavelengths in the analysis, a selection of analyte-characteristic-wavelengths to be used simultaneously during said analyte measurement procedure (78), and a selection of one or more main frequencies of the modulation of said excitation radiation (18) intensity to be used during said analyte measurement procedure (78) is determined.

A method of analyzing a material (12) comprising at least one analyte, wherein analyte-wavelength-specific measurements are interspersed with reference measurements (80), and wherein response signals obtained for the reference measurements (80) are used for one or more of calibrating an excitation radiation source (26) for generating said excitation radiation, calibrating said detection device, recognizing a variation in the measurement conditions by comparing results of individual reference measurements (80), adapting the analyte measurement procedure (78) with respect to one or more of the entire duration thereof, the absolute or relative duration of analyte-wavelength-specific measurements for a given analyte-characteristic-wavelength, or terminating and/or restarting the analyte measurement procedure, and adapting the analysis carried out in the analyzing step.

Disclosed herein is an apparatus (10) for analyzing a material (12) comprising at least one analyte, said apparatus (10) comprising a measurement body (16) having a contact surface (14) suitable to be brought in thermal contact or pressure-transmitting contact with said material (12), an excitation radiation source configured for irradiating excitation radiation into the material (12) to be absorbed therein, and a detection light source for generating a detection light beam (22) travelling through at least a portion of said measurement body (16) or a component included in said measurement body, wherein said detection light beam is directed to be totally or partially reflected at said contact surface (14), wherein said contact surface (14) of the measurement body is curved in at least one principal direction in the area where the detection light beam (22) is reflected.

A planar waveguide device (PWD) for interacting with a fluid (FLD) is disclosed, the planar waveguide device (PWD) comprising a waveguide layer (WGL) for supporting optical confinement, a coupling arrangement (CPA) for in-coupling and out-coupling of light into and from the waveguide layer (WGL), a fluid zone (FZN) for accommodating the fluid (FLD), a filter layer (FTL) arranged between the fluid zone (FZN) and the waveguide layer (WGL) in an interaction region (IAR) of the waveguide layer (WGL),
wherein the filter layer (FTL) comprises filter openings (FOP) arranged to allow the fluid (FLD) to interact with an evanescent field of light guided by the waveguide layer (WGL),
wherein the filter openings (FOP) are adapted to prevent particles (PAR) larger than a predefined size from interacting with said evanescent field,
wherein the filter openings (FOP) are arranged as line openings having their longitudinal direction in parallel with the direction of propagation (DOP) of light guided by the waveguide layer (WGL).